Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| P | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| P | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | CAT |
| Number of Residues | 3 |
| Details | IN THIS INACTIVE ZYMOGEN STRUCTURE THE NZ ATOM OF LYS P 37 SITS BETWEEN THE ACTIVE SITE CARBOXYLATES OF ASP B 32 AND ASP B 217, THEREBY PREVENTING CATALYSIS |
| Chain | Residue |
| P | LYS37 |
| P | TYR32 |
| B | ASP217 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VLFDTGSSNLWV |
| Chain | Residue | Details |
| B | VAL29-VAL40 | |
| B | ALA214-VAL225 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Propeptide: {"description":"Activation peptide","featureId":"PRO_0000026056"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 312 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP32 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP217 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER35 | |
| B | ASP32 | |
| B | THR220 | |
| B | ASP217 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR218 | |
| B | ASP32 | |
| B | THR33 | |
| B | ASP217 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER35 | |
| B | ASP32 | |
| B | ASP217 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | TYR75 | |
| B | SER35 | |
| B | ASP32 | |
| B | ASP217 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP32 | |
| B | THR220 | |
| B | THR33 | |
| B | ASP217 | |
