Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1HTQ

Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0001968	molecular_function	fibronectin binding
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005525	molecular_function	GTP binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006542	biological_process	glutamine biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0010756	biological_process	positive regulation of plasminogen activation
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0019003	molecular_function	GDP binding
A	0019740	biological_process	nitrogen utilization
A	0030145	molecular_function	manganese ion binding
A	0035375	molecular_function	zymogen binding
A	0043531	molecular_function	ADP binding
A	0046872	molecular_function	metal ion binding
A	0050897	molecular_function	cobalt ion binding
A	0051260	biological_process	protein homooligomerization
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0001968	molecular_function	fibronectin binding
B	0003824	molecular_function	catalytic activity
B	0004356	molecular_function	glutamine synthetase activity
B	0005524	molecular_function	ATP binding
B	0005525	molecular_function	GTP binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006542	biological_process	glutamine biosynthetic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0010756	biological_process	positive regulation of plasminogen activation
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0019003	molecular_function	GDP binding
B	0019740	biological_process	nitrogen utilization
B	0030145	molecular_function	manganese ion binding
B	0035375	molecular_function	zymogen binding
B	0043531	molecular_function	ADP binding
B	0046872	molecular_function	metal ion binding
B	0050897	molecular_function	cobalt ion binding
B	0051260	biological_process	protein homooligomerization
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0001968	molecular_function	fibronectin binding
C	0003824	molecular_function	catalytic activity
C	0004356	molecular_function	glutamine synthetase activity
C	0005524	molecular_function	ATP binding
C	0005525	molecular_function	GTP binding
C	0005576	cellular_component	extracellular region
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006542	biological_process	glutamine biosynthetic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0010756	biological_process	positive regulation of plasminogen activation
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0019003	molecular_function	GDP binding
C	0019740	biological_process	nitrogen utilization
C	0030145	molecular_function	manganese ion binding
C	0035375	molecular_function	zymogen binding
C	0043531	molecular_function	ADP binding
C	0046872	molecular_function	metal ion binding
C	0050897	molecular_function	cobalt ion binding
C	0051260	biological_process	protein homooligomerization
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0001968	molecular_function	fibronectin binding
D	0003824	molecular_function	catalytic activity
D	0004356	molecular_function	glutamine synthetase activity
D	0005524	molecular_function	ATP binding
D	0005525	molecular_function	GTP binding
D	0005576	cellular_component	extracellular region
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006542	biological_process	glutamine biosynthetic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0010756	biological_process	positive regulation of plasminogen activation
D	0016020	cellular_component	membrane
D	0016874	molecular_function	ligase activity
D	0019003	molecular_function	GDP binding
D	0019740	biological_process	nitrogen utilization
D	0030145	molecular_function	manganese ion binding
D	0035375	molecular_function	zymogen binding
D	0043531	molecular_function	ADP binding
D	0046872	molecular_function	metal ion binding
D	0050897	molecular_function	cobalt ion binding
D	0051260	biological_process	protein homooligomerization
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0001968	molecular_function	fibronectin binding
E	0003824	molecular_function	catalytic activity
E	0004356	molecular_function	glutamine synthetase activity
E	0005524	molecular_function	ATP binding
E	0005525	molecular_function	GTP binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006542	biological_process	glutamine biosynthetic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0010756	biological_process	positive regulation of plasminogen activation
E	0016020	cellular_component	membrane
E	0016874	molecular_function	ligase activity
E	0019003	molecular_function	GDP binding
E	0019740	biological_process	nitrogen utilization
E	0030145	molecular_function	manganese ion binding
E	0035375	molecular_function	zymogen binding
E	0043531	molecular_function	ADP binding
E	0046872	molecular_function	metal ion binding
E	0050897	molecular_function	cobalt ion binding
E	0051260	biological_process	protein homooligomerization
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0001968	molecular_function	fibronectin binding
F	0003824	molecular_function	catalytic activity
F	0004356	molecular_function	glutamine synthetase activity
F	0005524	molecular_function	ATP binding
F	0005525	molecular_function	GTP binding
F	0005576	cellular_component	extracellular region
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006542	biological_process	glutamine biosynthetic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0010756	biological_process	positive regulation of plasminogen activation
F	0016020	cellular_component	membrane
F	0016874	molecular_function	ligase activity
F	0019003	molecular_function	GDP binding
F	0019740	biological_process	nitrogen utilization
F	0030145	molecular_function	manganese ion binding
F	0035375	molecular_function	zymogen binding
F	0043531	molecular_function	ADP binding
F	0046872	molecular_function	metal ion binding
F	0050897	molecular_function	cobalt ion binding
F	0051260	biological_process	protein homooligomerization
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0001968	molecular_function	fibronectin binding
G	0003824	molecular_function	catalytic activity
G	0004356	molecular_function	glutamine synthetase activity
G	0005524	molecular_function	ATP binding
G	0005525	molecular_function	GTP binding
G	0005576	cellular_component	extracellular region
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006542	biological_process	glutamine biosynthetic process
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0010756	biological_process	positive regulation of plasminogen activation
G	0016020	cellular_component	membrane
G	0016874	molecular_function	ligase activity
G	0019003	molecular_function	GDP binding
G	0019740	biological_process	nitrogen utilization
G	0030145	molecular_function	manganese ion binding
G	0035375	molecular_function	zymogen binding
G	0043531	molecular_function	ADP binding
G	0046872	molecular_function	metal ion binding
G	0050897	molecular_function	cobalt ion binding
G	0051260	biological_process	protein homooligomerization
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0001968	molecular_function	fibronectin binding
H	0003824	molecular_function	catalytic activity
H	0004356	molecular_function	glutamine synthetase activity
H	0005524	molecular_function	ATP binding
H	0005525	molecular_function	GTP binding
H	0005576	cellular_component	extracellular region
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006542	biological_process	glutamine biosynthetic process
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0010756	biological_process	positive regulation of plasminogen activation
H	0016020	cellular_component	membrane
H	0016874	molecular_function	ligase activity
H	0019003	molecular_function	GDP binding
H	0019740	biological_process	nitrogen utilization
H	0030145	molecular_function	manganese ion binding
H	0035375	molecular_function	zymogen binding
H	0043531	molecular_function	ADP binding
H	0046872	molecular_function	metal ion binding
H	0050897	molecular_function	cobalt ion binding
H	0051260	biological_process	protein homooligomerization
I	0000166	molecular_function	nucleotide binding
I	0000287	molecular_function	magnesium ion binding
I	0001968	molecular_function	fibronectin binding
I	0003824	molecular_function	catalytic activity
I	0004356	molecular_function	glutamine synthetase activity
I	0005524	molecular_function	ATP binding
I	0005525	molecular_function	GTP binding
I	0005576	cellular_component	extracellular region
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006542	biological_process	glutamine biosynthetic process
I	0009274	cellular_component	peptidoglycan-based cell wall
I	0010756	biological_process	positive regulation of plasminogen activation
I	0016020	cellular_component	membrane
I	0016874	molecular_function	ligase activity
I	0019003	molecular_function	GDP binding
I	0019740	biological_process	nitrogen utilization
I	0030145	molecular_function	manganese ion binding
I	0035375	molecular_function	zymogen binding
I	0043531	molecular_function	ADP binding
I	0046872	molecular_function	metal ion binding
I	0050897	molecular_function	cobalt ion binding
I	0051260	biological_process	protein homooligomerization
J	0000166	molecular_function	nucleotide binding
J	0000287	molecular_function	magnesium ion binding
J	0001968	molecular_function	fibronectin binding
J	0003824	molecular_function	catalytic activity
J	0004356	molecular_function	glutamine synthetase activity
J	0005524	molecular_function	ATP binding
J	0005525	molecular_function	GTP binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006542	biological_process	glutamine biosynthetic process
J	0009274	cellular_component	peptidoglycan-based cell wall
J	0010756	biological_process	positive regulation of plasminogen activation
J	0016020	cellular_component	membrane
J	0016874	molecular_function	ligase activity
J	0019003	molecular_function	GDP binding
J	0019740	biological_process	nitrogen utilization
J	0030145	molecular_function	manganese ion binding
J	0035375	molecular_function	zymogen binding
J	0043531	molecular_function	ADP binding
J	0046872	molecular_function	metal ion binding
J	0050897	molecular_function	cobalt ion binding
J	0051260	biological_process	protein homooligomerization
K	0000166	molecular_function	nucleotide binding
K	0000287	molecular_function	magnesium ion binding
K	0001968	molecular_function	fibronectin binding
K	0003824	molecular_function	catalytic activity
K	0004356	molecular_function	glutamine synthetase activity
K	0005524	molecular_function	ATP binding
K	0005525	molecular_function	GTP binding
K	0005576	cellular_component	extracellular region
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006542	biological_process	glutamine biosynthetic process
K	0009274	cellular_component	peptidoglycan-based cell wall
K	0010756	biological_process	positive regulation of plasminogen activation
K	0016020	cellular_component	membrane
K	0016874	molecular_function	ligase activity
K	0019003	molecular_function	GDP binding
K	0019740	biological_process	nitrogen utilization
K	0030145	molecular_function	manganese ion binding
K	0035375	molecular_function	zymogen binding
K	0043531	molecular_function	ADP binding
K	0046872	molecular_function	metal ion binding
K	0050897	molecular_function	cobalt ion binding
K	0051260	biological_process	protein homooligomerization
L	0000166	molecular_function	nucleotide binding
L	0000287	molecular_function	magnesium ion binding
L	0001968	molecular_function	fibronectin binding
L	0003824	molecular_function	catalytic activity
L	0004356	molecular_function	glutamine synthetase activity
L	0005524	molecular_function	ATP binding
L	0005525	molecular_function	GTP binding
L	0005576	cellular_component	extracellular region
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006542	biological_process	glutamine biosynthetic process
L	0009274	cellular_component	peptidoglycan-based cell wall
L	0010756	biological_process	positive regulation of plasminogen activation
L	0016020	cellular_component	membrane
L	0016874	molecular_function	ligase activity
L	0019003	molecular_function	GDP binding
L	0019740	biological_process	nitrogen utilization
L	0030145	molecular_function	manganese ion binding
L	0035375	molecular_function	zymogen binding
L	0043531	molecular_function	ADP binding
L	0046872	molecular_function	metal ion binding
L	0050897	molecular_function	cobalt ion binding
L	0051260	biological_process	protein homooligomerization
M	0000166	molecular_function	nucleotide binding
M	0000287	molecular_function	magnesium ion binding
M	0001968	molecular_function	fibronectin binding
M	0003824	molecular_function	catalytic activity
M	0004356	molecular_function	glutamine synthetase activity
M	0005524	molecular_function	ATP binding
M	0005525	molecular_function	GTP binding
M	0005576	cellular_component	extracellular region
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006542	biological_process	glutamine biosynthetic process
M	0009274	cellular_component	peptidoglycan-based cell wall
M	0010756	biological_process	positive regulation of plasminogen activation
M	0016020	cellular_component	membrane
M	0016874	molecular_function	ligase activity
M	0019003	molecular_function	GDP binding
M	0019740	biological_process	nitrogen utilization
M	0030145	molecular_function	manganese ion binding
M	0035375	molecular_function	zymogen binding
M	0043531	molecular_function	ADP binding
M	0046872	molecular_function	metal ion binding
M	0050897	molecular_function	cobalt ion binding
M	0051260	biological_process	protein homooligomerization
N	0000166	molecular_function	nucleotide binding
N	0000287	molecular_function	magnesium ion binding
N	0001968	molecular_function	fibronectin binding
N	0003824	molecular_function	catalytic activity
N	0004356	molecular_function	glutamine synthetase activity
N	0005524	molecular_function	ATP binding
N	0005525	molecular_function	GTP binding
N	0005576	cellular_component	extracellular region
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0006542	biological_process	glutamine biosynthetic process
N	0009274	cellular_component	peptidoglycan-based cell wall
N	0010756	biological_process	positive regulation of plasminogen activation
N	0016020	cellular_component	membrane
N	0016874	molecular_function	ligase activity
N	0019003	molecular_function	GDP binding
N	0019740	biological_process	nitrogen utilization
N	0030145	molecular_function	manganese ion binding
N	0035375	molecular_function	zymogen binding
N	0043531	molecular_function	ADP binding
N	0046872	molecular_function	metal ion binding
N	0050897	molecular_function	cobalt ion binding
N	0051260	biological_process	protein homooligomerization
O	0000166	molecular_function	nucleotide binding
O	0000287	molecular_function	magnesium ion binding
O	0001968	molecular_function	fibronectin binding
O	0003824	molecular_function	catalytic activity
O	0004356	molecular_function	glutamine synthetase activity
O	0005524	molecular_function	ATP binding
O	0005525	molecular_function	GTP binding
O	0005576	cellular_component	extracellular region
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006542	biological_process	glutamine biosynthetic process
O	0009274	cellular_component	peptidoglycan-based cell wall
O	0010756	biological_process	positive regulation of plasminogen activation
O	0016020	cellular_component	membrane
O	0016874	molecular_function	ligase activity
O	0019003	molecular_function	GDP binding
O	0019740	biological_process	nitrogen utilization
O	0030145	molecular_function	manganese ion binding
O	0035375	molecular_function	zymogen binding
O	0043531	molecular_function	ADP binding
O	0046872	molecular_function	metal ion binding
O	0050897	molecular_function	cobalt ion binding
O	0051260	biological_process	protein homooligomerization
P	0000166	molecular_function	nucleotide binding
P	0000287	molecular_function	magnesium ion binding
P	0001968	molecular_function	fibronectin binding
P	0003824	molecular_function	catalytic activity
P	0004356	molecular_function	glutamine synthetase activity
P	0005524	molecular_function	ATP binding
P	0005525	molecular_function	GTP binding
P	0005576	cellular_component	extracellular region
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006542	biological_process	glutamine biosynthetic process
P	0009274	cellular_component	peptidoglycan-based cell wall
P	0010756	biological_process	positive regulation of plasminogen activation
P	0016020	cellular_component	membrane
P	0016874	molecular_function	ligase activity
P	0019003	molecular_function	GDP binding
P	0019740	biological_process	nitrogen utilization
P	0030145	molecular_function	manganese ion binding
P	0035375	molecular_function	zymogen binding
P	0043531	molecular_function	ADP binding
P	0046872	molecular_function	metal ion binding
P	0050897	molecular_function	cobalt ion binding
P	0051260	biological_process	protein homooligomerization
Q	0000166	molecular_function	nucleotide binding
Q	0000287	molecular_function	magnesium ion binding
Q	0001968	molecular_function	fibronectin binding
Q	0003824	molecular_function	catalytic activity
Q	0004356	molecular_function	glutamine synthetase activity
Q	0005524	molecular_function	ATP binding
Q	0005525	molecular_function	GTP binding
Q	0005576	cellular_component	extracellular region
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0006542	biological_process	glutamine biosynthetic process
Q	0009274	cellular_component	peptidoglycan-based cell wall
Q	0010756	biological_process	positive regulation of plasminogen activation
Q	0016020	cellular_component	membrane
Q	0016874	molecular_function	ligase activity
Q	0019003	molecular_function	GDP binding
Q	0019740	biological_process	nitrogen utilization
Q	0030145	molecular_function	manganese ion binding
Q	0035375	molecular_function	zymogen binding
Q	0043531	molecular_function	ADP binding
Q	0046872	molecular_function	metal ion binding
Q	0050897	molecular_function	cobalt ion binding
Q	0051260	biological_process	protein homooligomerization
R	0000166	molecular_function	nucleotide binding
R	0000287	molecular_function	magnesium ion binding
R	0001968	molecular_function	fibronectin binding
R	0003824	molecular_function	catalytic activity
R	0004356	molecular_function	glutamine synthetase activity
R	0005524	molecular_function	ATP binding
R	0005525	molecular_function	GTP binding
R	0005576	cellular_component	extracellular region
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0006542	biological_process	glutamine biosynthetic process
R	0009274	cellular_component	peptidoglycan-based cell wall
R	0010756	biological_process	positive regulation of plasminogen activation
R	0016020	cellular_component	membrane
R	0016874	molecular_function	ligase activity
R	0019003	molecular_function	GDP binding
R	0019740	biological_process	nitrogen utilization
R	0030145	molecular_function	manganese ion binding
R	0035375	molecular_function	zymogen binding
R	0043531	molecular_function	ADP binding
R	0046872	molecular_function	metal ion binding
R	0050897	molecular_function	cobalt ion binding
R	0051260	biological_process	protein homooligomerization
S	0000166	molecular_function	nucleotide binding
S	0000287	molecular_function	magnesium ion binding
S	0001968	molecular_function	fibronectin binding
S	0003824	molecular_function	catalytic activity
S	0004356	molecular_function	glutamine synthetase activity
S	0005524	molecular_function	ATP binding
S	0005525	molecular_function	GTP binding
S	0005576	cellular_component	extracellular region
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005886	cellular_component	plasma membrane
S	0006542	biological_process	glutamine biosynthetic process
S	0009274	cellular_component	peptidoglycan-based cell wall
S	0010756	biological_process	positive regulation of plasminogen activation
S	0016020	cellular_component	membrane
S	0016874	molecular_function	ligase activity
S	0019003	molecular_function	GDP binding
S	0019740	biological_process	nitrogen utilization
S	0030145	molecular_function	manganese ion binding
S	0035375	molecular_function	zymogen binding
S	0043531	molecular_function	ADP binding
S	0046872	molecular_function	metal ion binding
S	0050897	molecular_function	cobalt ion binding
S	0051260	biological_process	protein homooligomerization
T	0000166	molecular_function	nucleotide binding
T	0000287	molecular_function	magnesium ion binding
T	0001968	molecular_function	fibronectin binding
T	0003824	molecular_function	catalytic activity
T	0004356	molecular_function	glutamine synthetase activity
T	0005524	molecular_function	ATP binding
T	0005525	molecular_function	GTP binding
T	0005576	cellular_component	extracellular region
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005886	cellular_component	plasma membrane
T	0006542	biological_process	glutamine biosynthetic process
T	0009274	cellular_component	peptidoglycan-based cell wall
T	0010756	biological_process	positive regulation of plasminogen activation
T	0016020	cellular_component	membrane
T	0016874	molecular_function	ligase activity
T	0019003	molecular_function	GDP binding
T	0019740	biological_process	nitrogen utilization
T	0030145	molecular_function	manganese ion binding
T	0035375	molecular_function	zymogen binding
T	0043531	molecular_function	ADP binding
T	0046872	molecular_function	metal ion binding
T	0050897	molecular_function	cobalt ion binding
T	0051260	biological_process	protein homooligomerization
U	0000166	molecular_function	nucleotide binding
U	0000287	molecular_function	magnesium ion binding
U	0001968	molecular_function	fibronectin binding
U	0003824	molecular_function	catalytic activity
U	0004356	molecular_function	glutamine synthetase activity
U	0005524	molecular_function	ATP binding
U	0005525	molecular_function	GTP binding
U	0005576	cellular_component	extracellular region
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005886	cellular_component	plasma membrane
U	0006542	biological_process	glutamine biosynthetic process
U	0009274	cellular_component	peptidoglycan-based cell wall
U	0010756	biological_process	positive regulation of plasminogen activation
U	0016020	cellular_component	membrane
U	0016874	molecular_function	ligase activity
U	0019003	molecular_function	GDP binding
U	0019740	biological_process	nitrogen utilization
U	0030145	molecular_function	manganese ion binding
U	0035375	molecular_function	zymogen binding
U	0043531	molecular_function	ADP binding
U	0046872	molecular_function	metal ion binding
U	0050897	molecular_function	cobalt ion binding
U	0051260	biological_process	protein homooligomerization
V	0000166	molecular_function	nucleotide binding
V	0000287	molecular_function	magnesium ion binding
V	0001968	molecular_function	fibronectin binding
V	0003824	molecular_function	catalytic activity
V	0004356	molecular_function	glutamine synthetase activity
V	0005524	molecular_function	ATP binding
V	0005525	molecular_function	GTP binding
V	0005576	cellular_component	extracellular region
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005886	cellular_component	plasma membrane
V	0006542	biological_process	glutamine biosynthetic process
V	0009274	cellular_component	peptidoglycan-based cell wall
V	0010756	biological_process	positive regulation of plasminogen activation
V	0016020	cellular_component	membrane
V	0016874	molecular_function	ligase activity
V	0019003	molecular_function	GDP binding
V	0019740	biological_process	nitrogen utilization
V	0030145	molecular_function	manganese ion binding
V	0035375	molecular_function	zymogen binding
V	0043531	molecular_function	ADP binding
V	0046872	molecular_function	metal ion binding
V	0050897	molecular_function	cobalt ion binding
V	0051260	biological_process	protein homooligomerization
W	0000166	molecular_function	nucleotide binding
W	0000287	molecular_function	magnesium ion binding
W	0001968	molecular_function	fibronectin binding
W	0003824	molecular_function	catalytic activity
W	0004356	molecular_function	glutamine synthetase activity
W	0005524	molecular_function	ATP binding
W	0005525	molecular_function	GTP binding
W	0005576	cellular_component	extracellular region
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0006542	biological_process	glutamine biosynthetic process
W	0009274	cellular_component	peptidoglycan-based cell wall
W	0010756	biological_process	positive regulation of plasminogen activation
W	0016020	cellular_component	membrane
W	0016874	molecular_function	ligase activity
W	0019003	molecular_function	GDP binding
W	0019740	biological_process	nitrogen utilization
W	0030145	molecular_function	manganese ion binding
W	0035375	molecular_function	zymogen binding
W	0043531	molecular_function	ADP binding
W	0046872	molecular_function	metal ion binding
W	0050897	molecular_function	cobalt ion binding
W	0051260	biological_process	protein homooligomerization
X	0000166	molecular_function	nucleotide binding
X	0000287	molecular_function	magnesium ion binding
X	0001968	molecular_function	fibronectin binding
X	0003824	molecular_function	catalytic activity
X	0004356	molecular_function	glutamine synthetase activity
X	0005524	molecular_function	ATP binding
X	0005525	molecular_function	GTP binding
X	0005576	cellular_component	extracellular region
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005886	cellular_component	plasma membrane
X	0006542	biological_process	glutamine biosynthetic process
X	0009274	cellular_component	peptidoglycan-based cell wall
X	0010756	biological_process	positive regulation of plasminogen activation
X	0016020	cellular_component	membrane
X	0016874	molecular_function	ligase activity
X	0019003	molecular_function	GDP binding
X	0019740	biological_process	nitrogen utilization
X	0030145	molecular_function	manganese ion binding
X	0035375	molecular_function	zymogen binding
X	0043531	molecular_function	ADP binding
X	0046872	molecular_function	metal ion binding
X	0050897	molecular_function	cobalt ion binding
X	0051260	biological_process	protein homooligomerization

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 470

Chain	Residue
A	GLU129
A	ARG344
A	GLU357
A	ARG359
A	AMP7475

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 470

Chain	Residue
B	AMP7477
B	GLU129
B	ARG344
B	GLU357
B	ARG359

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 470

Chain	Residue
C	GLU129
C	ARG344
C	GLU357
C	ARG359
C	AMP7479

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 470

Chain	Residue
D	GLU129
D	ARG344
D	GLU357
D	ARG359
D	AMP7481

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN E 470

Chain	Residue
E	GLU129
E	ARG344
E	GLU357
E	ARG359
E	AMP7483

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN F 470

Chain	Residue
F	GLU129
F	ARG344
F	GLU357
F	ARG359
F	AMP7485

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN G 470

Chain	Residue
G	GLU129
G	ARG344
G	GLU357
G	ARG359
G	AMP7487

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 470

Chain	Residue
H	GLU129
H	ARG344
H	GLU357
H	ARG359
H	AMP7489

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN I 470

Chain	Residue
I	GLU129
I	ARG344
I	GLU357
I	ARG359
I	AMP7491

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN J 470

Chain	Residue
J	GLU129
J	ARG344
J	GLU357
J	ARG359
J	AMP7493

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN K 470

Chain	Residue
K	GLU129
K	ARG344
K	GLU357
K	ARG359
K	AMP7495

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN L 470

Chain	Residue
L	GLU129
L	ARG344
L	GLU357
L	ARG359
L	AMP7497

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN M 470

Chain	Residue
M	GLU129
M	ARG344
M	GLU357
M	ARG359
M	AMP7499

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN N 470

Chain	Residue
N	GLU129
N	ARG344
N	GLU357
N	ARG359
N	AMP7501

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN O 470

Chain	Residue
O	GLU129
O	ARG344
O	GLU357
O	ARG359
O	AMP7503

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN P 470

Chain	Residue
P	GLU129
P	ARG344
P	GLU357
P	ARG359
P	AMP7505

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN Q 470

Chain	Residue
Q	GLU129
Q	ARG344
Q	GLU357
Q	ARG359
Q	AMP7507

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN R 470

Chain	Residue
R	GLU129
R	ARG344
R	GLU357
R	ARG359
R	AMP7509

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN S 470

Chain	Residue
S	GLU129
S	ARG344
S	GLU357
S	ARG359
S	AMP7511

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN T 470

Chain	Residue
T	AMP7513
T	GLU129
T	ARG344
T	GLU357
T	ARG359

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN U 470

Chain	Residue
U	GLU129
U	ARG344
U	GLU357
U	ARG359
U	AMP7515

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN V 470

Chain	Residue
V	GLU129
V	ARG344
V	GLU357
V	ARG359
V	AMP7517

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN W 470

Chain	Residue
W	GLU129
W	ARG344
W	GLU357
W	ARG359
W	AMP7519

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN X 470

Chain	Residue
X	GLU129
X	ARG344
X	GLU357
X	ARG359
X	AMP7521

site_id	CC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP A 7475

Chain	Residue
A	TYR125
A	GLY127
A	GLU129
A	GLY209
A	ASN222
A	TYR223
A	GLN224
A	PHE225
A	HIS271
A	SER273
A	TRP275
A	ARG344
A	LYS352
A	ARG355
A	MN470
A	HOH7546
A	HOH7560

site_id	CC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT A 7476

Chain	Residue
A	GLU131
A	ASN264
A	GLY265
A	GLY267
A	HIS269
A	ARG321
A	TYR326
A	GLU327
A	ALA328
A	PRO329
A	HOH7651
A	HOH7714

site_id	CC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP B 7477

Chain	Residue
B	TYR125
B	GLY127
B	GLU129
B	GLY209
B	ASN222
B	TYR223
B	GLN224
B	PHE225
B	HIS271
B	SER273
B	TRP275
B	ARG344
B	LYS352
B	ARG355
B	MN470
B	HOH7557
B	HOH7571

site_id	DC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT B 7478

Chain	Residue
B	GLU131
B	ASN264
B	GLY265
B	GLY267
B	HIS269
B	ARG321
B	TYR326
B	GLU327
B	ALA328
B	PRO329
B	HOH7662
B	HOH7725

site_id	DC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP C 7479

Chain	Residue
C	TYR125
C	GLY127
C	GLU129
C	GLY209
C	ASN222
C	TYR223
C	GLN224
C	PHE225
C	HIS271
C	SER273
C	TRP275
C	ARG344
C	LYS352
C	ARG355
C	MN470
C	HOH7558
C	HOH7573

site_id	DC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT C 7480

Chain	Residue
C	GLU131
C	ASN264
C	GLY265
C	GLY267
C	HIS269
C	ARG321
C	TYR326
C	GLU327
C	ALA328
C	PRO329
C	HOH7663
C	HOH7726

site_id	DC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP D 7481

Chain	Residue
D	TYR125
D	GLY127
D	GLU129
D	GLY209
D	ASN222
D	TYR223
D	GLN224
D	PHE225
D	HIS271
D	SER273
D	TRP275
D	ARG344
D	LYS352
D	ARG355
D	MN470
D	HOH869
D	HOH884

site_id	DC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT D 7482

Chain	Residue
D	GLU131
D	ASN264
D	GLY265
D	GLY267
D	HIS269
D	ARG321
D	TYR326
D	GLU327
D	ALA328
D	PRO329
D	HOH985
D	HOH1052

site_id	DC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP E 7483

Chain	Residue
E	TYR125
E	GLY127
E	GLU129
E	GLY209
E	ASN222
E	TYR223
E	GLN224
E	PHE225
E	HIS271
E	SER273
E	TRP275
E	ARG344
E	LYS352
E	ARG355
E	MN470
E	HOH1132
E	HOH1147

site_id	DC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT E 7484

Chain	Residue
E	GLU131
E	ASN264
E	GLY265
E	GLY267
E	HIS269
E	ARG321
E	TYR326
E	GLU327
E	ALA328
E	PRO329
E	HOH1248
E	HOH1315

site_id	DC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP F 7485

Chain	Residue
F	TYR125
F	GLY127
F	GLU129
F	GLY209
F	ASN222
F	TYR223
F	GLN224
F	PHE225
F	HIS271
F	SER273
F	TRP275
F	ARG344
F	LYS352
F	ARG355
F	MN470
F	HOH7567
F	HOH7581

site_id	DC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT F 7486

Chain	Residue
F	GLU131
F	ASN264
F	GLY265
F	GLY267
F	HIS269
F	ARG321
F	TYR326
F	GLU327
F	ALA328
F	PRO329
F	HOH7672
F	HOH7735

site_id	EC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP G 7487

Chain	Residue
G	TYR125
G	GLY127
G	GLU129
G	GLY209
G	ASN222
G	TYR223
G	GLN224
G	PHE225
G	HIS271
G	SER273
G	TRP275
G	ARG344
G	LYS352
G	ARG355
G	MN470
G	HOH7574
G	HOH7588

site_id	EC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT G 7488

Chain	Residue
G	GLU131
G	ASN264
G	GLY265
G	GLY267
G	HIS269
G	ARG321
G	TYR326
G	GLU327
G	ALA328
G	PRO329
G	HOH7678
G	HOH7741

site_id	EC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP H 7489

Chain	Residue
H	TYR125
H	GLY127
H	GLU129
H	GLY209
H	ASN222
H	TYR223
H	GLN224
H	PHE225
H	HIS271
H	SER273
H	TRP275
H	ARG344
H	LYS352
H	ARG355
H	MN470
H	HOH7577
H	HOH7590

site_id	EC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT H 7490

Chain	Residue
H	GLU131
H	ASN264
H	GLY265
H	GLY267
H	HIS269
H	ARG321
H	TYR326
H	GLU327
H	ALA328
H	PRO329
H	HOH7679
H	HOH7743

site_id	EC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP I 7491

Chain	Residue
I	TYR125
I	GLY127
I	GLU129
I	GLY209
I	ASN222
I	TYR223
I	GLN224
I	PHE225
I	HIS271
I	SER273
I	TRP275
I	ARG344
I	LYS352
I	ARG355
I	MN470
I	HOH7580
I	HOH7594

site_id	EC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT I 7492

Chain	Residue
I	GLU131
I	ASN264
I	GLY265
I	GLY267
I	HIS269
I	ARG321
I	TYR326
I	GLU327
I	ALA328
I	PRO329
I	HOH7684
I	HOH7748

site_id	EC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP J 7493

Chain	Residue
J	TYR125
J	GLY127
J	GLU129
J	GLY209
J	ASN222
J	TYR223
J	GLN224
J	PHE225
J	HIS271
J	SER273
J	TRP275
J	ARG344
J	LYS352
J	ARG355
J	MN470
J	HOH2447
J	HOH2462

site_id	EC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT J 7494

Chain	Residue
J	GLU131
J	ASN264
J	GLY265
J	GLY267
J	HIS269
J	ARG321
J	TYR326
J	GLU327
J	ALA328
J	PRO329
J	HOH2563
J	HOH2630

site_id	EC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP K 7495

Chain	Residue
K	TYR125
K	GLY127
K	GLU129
K	GLY209
K	ASN222
K	TYR223
K	GLN224
K	PHE225
K	HIS271
K	SER273
K	TRP275
K	ARG344
K	LYS352
K	ARG355
K	MN470
K	HOH2710
K	HOH2725

site_id	FC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT K 7496

Chain	Residue
K	GLU131
K	ASN264
K	GLY265
K	GLY267
K	HIS269
K	ARG321
K	TYR326
K	GLU327
K	ALA328
K	PRO329
K	HOH2826
K	HOH2893

site_id	FC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP L 7497

Chain	Residue
L	TYR125
L	GLY127
L	GLU129
L	GLY209
L	ASN222
L	TYR223
L	GLN224
L	PHE225
L	HIS271
L	SER273
L	TRP275
L	ARG344
L	LYS352
L	ARG355
L	MN470
L	HOH2973
L	HOH2988

site_id	FC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT L 7498

Chain	Residue
L	GLU131
L	ASN264
L	GLY265
L	GLY267
L	HIS269
L	ARG321
L	TYR326
L	GLU327
L	ALA328
L	PRO329
L	HOH3089
L	HOH3156

site_id	FC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP M 7499

Chain	Residue
M	TYR125
M	GLY127
M	GLU129
M	GLY209
M	ASN222
M	TYR223
M	GLN224
M	PHE225
M	HIS271
M	SER273
M	TRP275
M	ARG344
M	LYS352
M	ARG355
M	MN470
M	HOH3236
M	HOH3251

site_id	FC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT M 7500

Chain	Residue
M	GLU131
M	ASN264
M	GLY265
M	GLY267
M	HIS269
M	ARG321
M	TYR326
M	GLU327
M	ALA328
M	PRO329
M	HOH3352
M	HOH3419

site_id	FC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP N 7501

Chain	Residue
N	TYR125
N	GLY127
N	GLU129
N	GLY209
N	ASN222
N	TYR223
N	GLN224
N	PHE225
N	HIS271
N	SER273
N	TRP275
N	ARG344
N	LYS352
N	ARG355
N	MN470
N	HOH3499
N	HOH3514

site_id	FC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT N 7502

Chain	Residue
N	GLU131
N	ASN264
N	GLY265
N	GLY267
N	HIS269
N	ARG321
N	TYR326
N	GLU327
N	ALA328
N	PRO329
N	HOH3615
N	HOH3682

site_id	FC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP O 7503

Chain	Residue
O	TYR125
O	GLY127
O	GLU129
O	GLY209
O	ASN222
O	TYR223
O	GLN224
O	PHE225
O	HIS271
O	SER273
O	TRP275
O	ARG344
O	LYS352
O	ARG355
O	MN470
O	HOH3762
O	HOH3777

site_id	FC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT O 7504

Chain	Residue
O	GLU131
O	ASN264
O	GLY265
O	GLY267
O	HIS269
O	ARG321
O	TYR326
O	GLU327
O	ALA328
O	PRO329
O	HOH3878
O	HOH3945

site_id	GC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP P 7505

Chain	Residue
P	TYR125
P	GLY127
P	GLU129
P	GLY209
P	ASN222
P	TYR223
P	GLN224
P	PHE225
P	HIS271
P	SER273
P	TRP275
P	ARG344
P	LYS352
P	ARG355
P	MN470
P	HOH4025
P	HOH4040

site_id	GC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT P 7506

Chain	Residue
P	GLU131
P	ASN264
P	GLY265
P	GLY267
P	HIS269
P	ARG321
P	TYR326
P	GLU327
P	ALA328
P	PRO329
P	HOH4141
P	HOH4208

site_id	GC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP Q 7507

Chain	Residue
Q	TYR125
Q	GLY127
Q	GLU129
Q	GLY209
Q	ASN222
Q	TYR223
Q	GLN224
Q	PHE225
Q	HIS271
Q	SER273
Q	TRP275
Q	ARG344
Q	LYS352
Q	ARG355
Q	MN470
Q	HOH4288
Q	HOH4303

site_id	GC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT Q 7508

Chain	Residue
Q	GLU131
Q	ASN264
Q	GLY265
Q	GLY267
Q	HIS269
Q	ARG321
Q	TYR326
Q	GLU327
Q	ALA328
Q	PRO329
Q	HOH4404
Q	HOH4471

site_id	GC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP R 7509

Chain	Residue
R	TYR125
R	GLY127
R	GLU129
R	GLY209
R	ASN222
R	TYR223
R	GLN224
R	PHE225
R	HIS271
R	SER273
R	TRP275
R	ARG344
R	LYS352
R	ARG355
R	MN470
R	HOH4551
R	HOH4566

site_id	GC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT R 7510

Chain	Residue
R	GLU131
R	ASN264
R	GLY265
R	GLY267
R	HIS269
R	ARG321
R	TYR326
R	GLU327
R	ALA328
R	PRO329
R	HOH4667
R	HOH4734

site_id	GC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP S 7511

Chain	Residue
S	TYR125
S	GLY127
S	GLU129
S	GLY209
S	ASN222
S	TYR223
S	GLN224
S	PHE225
S	HIS271
S	SER273
S	TRP275
S	ARG344
S	LYS352
S	ARG355
S	MN470
S	HOH4814
S	HOH4829

site_id	GC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT S 7512

Chain	Residue
S	GLU131
S	ASN264
S	GLY265
S	GLY267
S	HIS269
S	ARG321
S	TYR326
S	GLU327
S	ALA328
S	PRO329
S	HOH4930
S	HOH4997

site_id	GC9
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP T 7513

Chain	Residue
T	TYR125
T	GLY127
T	GLU129
T	GLY209
T	ASN222
T	TYR223
T	GLN224
T	PHE225
T	HIS271
T	SER273
T	TRP275
T	ARG344
T	LYS352
T	ARG355
T	MN470
T	HOH5077
T	HOH5092

site_id	HC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT T 7514

Chain	Residue
T	GLU131
T	ASN264
T	GLY265
T	GLY267
T	HIS269
T	ARG321
T	TYR326
T	GLU327
T	ALA328
T	PRO329
T	HOH5193
T	HOH5260

site_id	HC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP U 7515

Chain	Residue
U	TYR125
U	GLY127
U	GLU129
U	GLY209
U	ASN222
U	TYR223
U	GLN224
U	PHE225
U	HIS271
U	SER273
U	TRP275
U	ARG344
U	LYS352
U	ARG355
U	MN470
U	HOH5340
U	HOH5355

site_id	HC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT U 7516

Chain	Residue
U	GLU131
U	ASN264
U	GLY265
U	GLY267
U	HIS269
U	ARG321
U	TYR326
U	GLU327
U	ALA328
U	PRO329
U	HOH5456
U	HOH5523

site_id	HC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP V 7517

Chain	Residue
V	TYR125
V	GLY127
V	GLU129
V	GLY209
V	ASN222
V	TYR223
V	GLN224
V	PHE225
V	HIS271
V	SER273
V	TRP275
V	ARG344
V	LYS352
V	ARG355
V	MN470
V	HOH5603
V	HOH5618

site_id	HC5
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT V 7518

Chain	Residue
V	GLU131
V	ASN264
V	GLY265
V	GLY267
V	HIS269
V	ARG321
V	TYR326
V	GLU327
V	ALA328
V	PRO329
V	HOH5719
V	HOH5786

site_id	HC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP W 7519

Chain	Residue
W	TYR125
W	GLY127
W	GLU129
W	GLY209
W	ASN222
W	TYR223
W	GLN224
W	PHE225
W	HIS271
W	SER273
W	TRP275
W	ARG344
W	LYS352
W	ARG355
W	MN470
W	HOH5866
W	HOH5881

site_id	HC7
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT W 7520

Chain	Residue
W	GLU131
W	ASN264
W	GLY265
W	GLY267
W	HIS269
W	ARG321
W	TYR326
W	GLU327
W	ALA328
W	PRO329
W	HOH5982
W	HOH6049

site_id	HC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE AMP X 7521

Chain	Residue
X	TYR125
X	GLY127
X	GLU129
X	GLY209
X	ASN222
X	TYR223
X	GLN224
X	PHE225
X	HIS271
X	SER273
X	TRP275
X	ARG344
X	LYS352
X	ARG355
X	MN470
X	HOH6129
X	HOH6144

site_id	HC9
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CIT X 7522

Chain	Residue
X	GLU131
X	ASN264
X	GLY265
X	GLY267
X	HIS269
X	ARG321
X	TYR326
X	GLU327
X	ALA328
X	PRO329
X	HOH6245
X	HOH6312

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSirgfqsihESDmlL

Chain	Residue	Details
A	PHE49-LEU67

site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPLfgd..NGSGmHchqS

Chain	Residue	Details
A	LYS258-SER273

site_id	PS00182
Number of Residues	13
Details	GLNA_ADENYLATION Glutamine synthetase class-I adenylation site. KIepqapVDKDLY

Chain	Residue	Details
A	LYS385-TYR397

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2016
Details	Domain: {"description":"GS beta-grasp","evidences":[{"source":"PROSITE-ProRule","id":"PRU01330","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8880
Details	Domain: {"description":"GS catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU01331","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	144
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16027359","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19695264","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22369127","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2012","firstPage":"620","lastPage":"626","volume":"3","journal":"Med. Chem. Commun.","title":"Synthesis, biological evaluation and X-Ray crystallographic studies of imidazo(1,2-A)pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors.","authors":["Nordqvist A.","Nilsson M.T.","Lagerlund O.","Muthas D.","Gising J.","Yahiaoui S.","Odell L.R.","Srinivasa B.R.","Larhed M.","Mowbray S.L.","Karlen A."],"citationCrossReferences":[{"database":"DOI","id":"10.1039/C2MD00310D"}]}},{"source":"PDB","id":"2BVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WHI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ACF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16027359","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2BVC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	144
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16027359","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"19695264","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22369127","evidenceCode":"ECO:0000305"},{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2012","firstPage":"620","lastPage":"626","volume":"3","journal":"Med. Chem. Commun.","title":"Synthesis, biological evaluation and X-Ray crystallographic studies of imidazo(1,2-A)pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors.","authors":["Nordqvist A.","Nilsson M.T.","Lagerlund O.","Muthas D.","Gising J.","Yahiaoui S.","Odell L.R.","Srinivasa B.R.","Larhed M.","Mowbray S.L.","Karlen A."],"citationCrossReferences":[{"database":"DOI","id":"10.1039/C2MD00310D"}]}},{"source":"PDB","id":"2BVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WHI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ACF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P12425","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P77961","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P0A1P6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16027359","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22369127","evidenceCode":"ECO:0000305"},{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2012","firstPage":"620","lastPage":"626","volume":"3","journal":"Med. Chem. Commun.","title":"Synthesis, biological evaluation and X-Ray crystallographic studies of imidazo(1,2-A)pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors.","authors":["Nordqvist A.","Nilsson M.T.","Lagerlund O.","Muthas D.","Gising J.","Yahiaoui S.","Odell L.R.","Srinivasa B.R.","Larhed M.","Mowbray S.L.","Karlen A."],"citationCrossReferences":[{"database":"DOI","id":"10.1039/C2MD00310D"}]}},{"source":"PDB","id":"2BVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZXV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ACF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	24
Details	Modified residue: {"description":"O-AMP-tyrosine","evidences":[{"source":"PubMed","id":"15037612","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12146952","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16027359","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
A	ARG339
A	ASP50
A	GLU327

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
J	ARG339
J	ASP50
J	GLU327

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
K	ARG339
K	ASP50
K	GLU327

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
L	ARG339
L	ASP50
L	GLU327

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
M	ARG339
M	ASP50
M	GLU327

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
N	ARG339
N	ASP50
N	GLU327

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
O	ARG339
O	ASP50
O	GLU327

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
P	ARG339
P	ASP50
P	GLU327

site_id	CSA17
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
Q	ARG339
Q	ASP50
Q	GLU327

site_id	CSA18
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
R	ARG339
R	ASP50
R	GLU327

site_id	CSA19
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
S	ARG339
S	ASP50
S	GLU327

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
B	ARG339
B	ASP50
B	GLU327

site_id	CSA20
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
T	ARG339
T	ASP50
T	GLU327

site_id	CSA21
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
U	ARG339
U	ASP50
U	GLU327

site_id	CSA22
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
V	ARG339
V	ASP50
V	GLU327

site_id	CSA23
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
W	ARG339
W	ASP50
W	GLU327

site_id	CSA24
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
X	ARG339
X	ASP50
X	GLU327

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
C	ARG339
C	ASP50
C	GLU327

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
D	ARG339
D	ASP50
D	GLU327

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
E	ARG339
E	ASP50
E	GLU327

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
F	ARG339
F	ASP50
F	GLU327

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
G	ARG339
G	ASP50
G	GLU327

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
H	ARG339
H	ASP50
H	GLU327

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1hto

Chain	Residue	Details
I	ARG339
I	ASP50
I	GLU327

site_id	MCSA1
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
A	ASP50	activator, proton acceptor
A	GLU129	metal ligand
A	GLU131	metal ligand
A	GLU212	metal ligand
A	GLU220	metal ligand
A	HIS269	metal ligand
A	ARG339	electrostatic stabiliser
A	GLU357	metal ligand
A	ARG359	electrostatic stabiliser

site_id	MCSA10
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
J	ASP50	activator, proton acceptor
J	GLU129	metal ligand
J	GLU131	metal ligand
J	GLU212	metal ligand
J	GLU220	metal ligand
J	HIS269	metal ligand
J	ARG339	electrostatic stabiliser
J	GLU357	metal ligand
J	ARG359	electrostatic stabiliser

site_id	MCSA11
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
K	ASP50	activator, proton acceptor
K	GLU129	metal ligand
K	GLU131	metal ligand
K	GLU212	metal ligand
K	GLU220	metal ligand
K	HIS269	metal ligand
K	ARG339	electrostatic stabiliser
K	GLU357	metal ligand
K	ARG359	electrostatic stabiliser

site_id	MCSA12
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
L	ASP50	activator, proton acceptor
L	GLU129	metal ligand
L	GLU131	metal ligand
L	GLU212	metal ligand
L	GLU220	metal ligand
L	HIS269	metal ligand
L	ARG339	electrostatic stabiliser
L	GLU357	metal ligand
L	ARG359	electrostatic stabiliser

site_id	MCSA13
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
M	ASP50	activator, proton acceptor
M	GLU129	metal ligand
M	GLU131	metal ligand
M	GLU212	metal ligand
M	GLU220	metal ligand
M	HIS269	metal ligand
M	ARG339	electrostatic stabiliser
M	GLU357	metal ligand
M	ARG359	electrostatic stabiliser

site_id	MCSA14
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
N	ASP50	activator, proton acceptor
N	GLU129	metal ligand
N	GLU131	metal ligand
N	GLU212	metal ligand
N	GLU220	metal ligand
N	HIS269	metal ligand
N	ARG339	electrostatic stabiliser
N	GLU357	metal ligand
N	ARG359	electrostatic stabiliser

site_id	MCSA15
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
O	ASP50	activator, proton acceptor
O	GLU129	metal ligand
O	GLU131	metal ligand
O	GLU212	metal ligand
O	GLU220	metal ligand
O	HIS269	metal ligand
O	ARG339	electrostatic stabiliser
O	GLU357	metal ligand
O	ARG359	electrostatic stabiliser

site_id	MCSA16
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
P	ASP50	activator, proton acceptor
P	GLU129	metal ligand
P	GLU131	metal ligand
P	GLU212	metal ligand
P	GLU220	metal ligand
P	HIS269	metal ligand
P	ARG339	electrostatic stabiliser
P	GLU357	metal ligand
P	ARG359	electrostatic stabiliser

site_id	MCSA17
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
Q	ASP50	activator, proton acceptor
Q	GLU129	metal ligand
Q	GLU131	metal ligand
Q	GLU212	metal ligand
Q	GLU220	metal ligand
Q	HIS269	metal ligand
Q	ARG339	electrostatic stabiliser
Q	GLU357	metal ligand
Q	ARG359	electrostatic stabiliser

site_id	MCSA18
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
R	ASP50	activator, proton acceptor
R	GLU129	metal ligand
R	GLU131	metal ligand
R	GLU212	metal ligand
R	GLU220	metal ligand
R	HIS269	metal ligand
R	ARG339	electrostatic stabiliser
R	GLU357	metal ligand
R	ARG359	electrostatic stabiliser

site_id	MCSA19
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
S	ASP50	activator, proton acceptor
S	GLU129	metal ligand
S	GLU131	metal ligand
S	GLU212	metal ligand
S	GLU220	metal ligand
S	HIS269	metal ligand
S	ARG339	electrostatic stabiliser
S	GLU357	metal ligand
S	ARG359	electrostatic stabiliser

site_id	MCSA2
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
B	ASP50	activator, proton acceptor
B	GLU129	metal ligand
B	GLU131	metal ligand
B	GLU212	metal ligand
B	GLU220	metal ligand
B	HIS269	metal ligand
B	ARG339	electrostatic stabiliser
B	GLU357	metal ligand
B	ARG359	electrostatic stabiliser

site_id	MCSA20
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
T	ASP50	activator, proton acceptor
T	GLU129	metal ligand
T	GLU131	metal ligand
T	GLU212	metal ligand
T	GLU220	metal ligand
T	HIS269	metal ligand
T	ARG339	electrostatic stabiliser
T	GLU357	metal ligand
T	ARG359	electrostatic stabiliser

site_id	MCSA21
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
U	ASP50	activator, proton acceptor
U	GLU129	metal ligand
U	GLU131	metal ligand
U	GLU212	metal ligand
U	GLU220	metal ligand
U	HIS269	metal ligand
U	ARG339	electrostatic stabiliser
U	GLU357	metal ligand
U	ARG359	electrostatic stabiliser

site_id	MCSA22
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
V	ASP50	activator, proton acceptor
V	GLU129	metal ligand
V	GLU131	metal ligand
V	GLU212	metal ligand
V	GLU220	metal ligand
V	HIS269	metal ligand
V	ARG339	electrostatic stabiliser
V	GLU357	metal ligand
V	ARG359	electrostatic stabiliser

site_id	MCSA23
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
W	ASP50	activator, proton acceptor
W	GLU129	metal ligand
W	GLU131	metal ligand
W	GLU212	metal ligand
W	GLU220	metal ligand
W	HIS269	metal ligand
W	ARG339	electrostatic stabiliser
W	GLU357	metal ligand
W	ARG359	electrostatic stabiliser

site_id	MCSA24
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
X	ASP50	activator, proton acceptor
X	GLU129	metal ligand
X	GLU131	metal ligand
X	GLU212	metal ligand
X	GLU220	metal ligand
X	HIS269	metal ligand
X	ARG339	electrostatic stabiliser
X	GLU357	metal ligand
X	ARG359	electrostatic stabiliser

site_id	MCSA3
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
C	ASP50	activator, proton acceptor
C	GLU129	metal ligand
C	GLU131	metal ligand
C	GLU212	metal ligand
C	GLU220	metal ligand
C	HIS269	metal ligand
C	ARG339	electrostatic stabiliser
C	GLU357	metal ligand
C	ARG359	electrostatic stabiliser

site_id	MCSA4
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
D	ASP50	activator, proton acceptor
D	GLU129	metal ligand
D	GLU131	metal ligand
D	GLU212	metal ligand
D	GLU220	metal ligand
D	HIS269	metal ligand
D	ARG339	electrostatic stabiliser
D	GLU357	metal ligand
D	ARG359	electrostatic stabiliser

site_id	MCSA5
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
E	ASP50	activator, proton acceptor
E	GLU129	metal ligand
E	GLU131	metal ligand
E	GLU212	metal ligand
E	GLU220	metal ligand
E	HIS269	metal ligand
E	ARG339	electrostatic stabiliser
E	GLU357	metal ligand
E	ARG359	electrostatic stabiliser

site_id	MCSA6
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
F	ASP50	activator, proton acceptor
F	GLU129	metal ligand
F	GLU131	metal ligand
F	GLU212	metal ligand
F	GLU220	metal ligand
F	HIS269	metal ligand
F	ARG339	electrostatic stabiliser
F	GLU357	metal ligand
F	ARG359	electrostatic stabiliser

site_id	MCSA7
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
G	ASP50	activator, proton acceptor
G	GLU129	metal ligand
G	GLU131	metal ligand
G	GLU212	metal ligand
G	GLU220	metal ligand
G	HIS269	metal ligand
G	ARG339	electrostatic stabiliser
G	GLU357	metal ligand
G	ARG359	electrostatic stabiliser

site_id	MCSA8
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
H	ASP50	activator, proton acceptor
H	GLU129	metal ligand
H	GLU131	metal ligand
H	GLU212	metal ligand
H	GLU220	metal ligand
H	HIS269	metal ligand
H	ARG339	electrostatic stabiliser
H	GLU357	metal ligand
H	ARG359	electrostatic stabiliser

site_id	MCSA9
Number of Residues	9
Details	M-CSA 537

Chain	Residue	Details
I	ASP50	activator, proton acceptor
I	GLU129	metal ligand
I	GLU131	metal ligand
I	GLU212	metal ligand
I	GLU220	metal ligand
I	HIS269	metal ligand
I	ARG339	electrostatic stabiliser
I	GLU357	metal ligand
I	ARG359	electrostatic stabiliser

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)