Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | HIS142 |
| A | HIS146 |
| A | HIS152 |
| A | HOH479 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | GLU9 |
| A | ASP93 |
| A | CYS197 |
| A | ASN200 |
| A | HOH416 |
| A | HOH430 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | HIS142 |
| B | HIS146 |
| B | HIS152 |
| B | HOH302 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | GLU9 |
| B | ASP93 |
| B | CYS197 |
| B | ASN200 |
| B | HOH349 |
| B | HOH357 |
| site_id | CAA |
| Number of Residues | 3 |
| Details | CALCIUM ION BINDING SITE IN CHAIN A |
| Chain | Residue |
| A | GLU9 |
| A | ASP93 |
| A | ASN200 |
| site_id | CAB |
| Number of Residues | 3 |
| Details | CALCIUM ION BINDING SITE IN CHAIN B |
| Chain | Residue |
| B | GLU9 |
| B | ASP93 |
| B | ASN200 |
| site_id | ZNA |
| Number of Residues | 3 |
| Details | ZINC BINDING SITE IN CHAIN A. THEY ARE IDENTIFIED BY CONSERVED RESIDUES HEXXHXXGXXH IN BOTH VENOM AND MAMMALIAN COLLAGENASES |
| Chain | Residue |
| A | HIS142 |
| A | HIS146 |
| A | HIS152 |
| site_id | ZNB |
| Number of Residues | 3 |
| Details | ZINC BINDING SITE IN CHAIN B. THEY ARE IDENTIFIED BY CONSERVED RESIDUES HEXXHXXGXXH IN BOTH VENOM AND MAMMALIAN COLLAGENASES |
| Chain | Residue |
| B | HIS142 |
| B | HIS146 |
| B | HIS152 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TMAHELGHNL |
| Chain | Residue | Details |
| A | THR139-LEU148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 392 |
| Details | Domain: {"description":"Peptidase M12B","evidences":[{"source":"PROSITE-ProRule","id":"PRU00276","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {} |
