1HSL
REFINED 1.89 ANGSTROMS STRUCTURE OF THE HISTIDINE-BINDING PROTEIN COMPLEXED WITH HISTIDINE AND ITS RELATIONSHIP WITH MANY OTHER ACTIVE TRANSPORT(SLASH)CHEMOSENSORY RECEPTORS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006865 | biological_process | amino acid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| A | 0071705 | biological_process | nitrogen compound transport |
| A | 1903810 | biological_process | L-histidine import across plasma membrane |
| B | 0006865 | biological_process | amino acid transport |
| B | 0016020 | cellular_component | membrane |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| B | 0071705 | biological_process | nitrogen compound transport |
| B | 1903810 | biological_process | L-histidine import across plasma membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 750 |
| Chain | Residue |
| A | ALA1 |
| A | GLU205 |
| A | HOH810 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 751 |
| Chain | Residue |
| A | ASP177 |
| A | HOH923 |
| B | ASP91 |
| B | GLU162 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 752 |
| Chain | Residue |
| A | ASP187 |
| A | GLU128 |
| A | HIS129 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 753 |
| Chain | Residue |
| A | GLU25 |
| B | GLU36 |
| B | HOH895 |
| B | HOH896 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 754 |
| Chain | Residue |
| A | ASP232 |
| A | HOH328 |
| B | ASP156 |
| B | HOH887 |
| B | HOH942 |
| B | HOH954 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 755 |
| Chain | Residue |
| A | ASP156 |
| A | HOH926 |
| A | HOH927 |
| B | ASP232 |
| B | HOH890 |
| B | HOH944 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 756 |
| Chain | Residue |
| A | HIS129 |
| A | HOH261 |
| A | HOH263 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HIS A 239 |
| Chain | Residue |
| A | LEU52 |
| A | SER69 |
| A | SER70 |
| A | LEU71 |
| A | SER72 |
| A | ARG77 |
| A | THR120 |
| A | THR121 |
| A | GLN122 |
| A | ASP161 |
| A | HOH240 |
| A | HOH242 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HIS B 239 |
| Chain | Residue |
| B | TYR14 |
| B | SER69 |
| B | SER70 |
| B | LEU71 |
| B | SER72 |
| B | ARG77 |
| B | THR120 |
| B | THR121 |
| B | GLN122 |
| B | ASP161 |
| B | HOH245 |
| B | HOH247 |
Functional Information from PROSITE/UniProt
| site_id | PS01039 |
| Number of Residues | 14 |
| Details | SBP_BACTERIAL_3 Bacterial extracellular solute-binding proteins, family 3 signature. GFDIDLAKeLCKRI |
| Chain | Residue | Details |
| A | GLY28-ILE41 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8161536","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HSL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
