1HRA

THE SOLUTION STRUCTURE OF THE HUMAN RETINOIC ACID RECEPTOR-BETA DNA-BINDING DOMAIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 81

Chain	Residue
A	CYS8
A	CYS11
A	CYS25
A	CYS28

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 82

Chain	Residue
A	CYS63
A	CYS44
A	ARG46
A	ASP47
A	CYS50
A	CYS60

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Functional Information from PROSITE/UniProt

site_id	PS00031
Number of Residues	27
Details	NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CfvCq.Dkssgy.HYgvsaCegCkgFFrR

Chain	Residue	Details
A	CYS8-ARG34

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	65
Details	DNA_BIND: Nuclear receptor => ECO:0000255|PROSITE-ProRule:PRU00407

Chain	Residue	Details
A	SER15-ASN80

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site_id	SWS_FT_FI2
Number of Residues	44
Details	ZN_FING: NR C4-type => ECO:0000255|PROSITE-ProRule:PRU00407

Chain	Residue	Details
A	SER15-SER35
A	VAL51-LYS75

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	VAL4

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