1HQK
CRYSTAL STRUCTURE ANALYSIS OF LUMAZINE SYNTHASE FROM AQUIFEX AEOLICUS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0009349 | cellular_component | riboflavin synthase complex |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0009349 | cellular_component | riboflavin synthase complex |
| B | 0016740 | molecular_function | transferase activity |
| C | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0009349 | cellular_component | riboflavin synthase complex |
| C | 0016740 | molecular_function | transferase activity |
| D | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0009349 | cellular_component | riboflavin synthase complex |
| D | 0016740 | molecular_function | transferase activity |
| E | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0009231 | biological_process | riboflavin biosynthetic process |
| E | 0009349 | cellular_component | riboflavin synthase complex |
| E | 0016740 | molecular_function | transferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS88 | |
| B | HIS88 | |
| C | HIS88 | |
| D | HIS88 | |
| E | HIS88 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PHE22 | |
| B | LYS135 | |
| C | PHE22 | |
| C | SER56 | |
| C | VAL80 | |
| C | PHE113 | |
| C | LYS135 | |
| D | PHE22 | |
| D | SER56 | |
| D | VAL80 | |
| D | PHE113 | |
| A | SER56 | |
| D | LYS135 | |
| E | PHE22 | |
| E | SER56 | |
| E | VAL80 | |
| E | PHE113 | |
| E | LYS135 | |
| A | VAL80 | |
| A | PHE113 | |
| A | LYS135 | |
| B | PHE22 | |
| B | SER56 | |
| B | VAL80 | |
| B | PHE113 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA85 | |
| E | ARG127 | |
| A | ARG127 | |
| B | ALA85 | |
| B | ARG127 | |
| C | ALA85 | |
| C | ARG127 | |
| D | ALA85 | |
| D | ARG127 | |
| E | ALA85 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| A | HIS88 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| B | HIS88 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| C | HIS88 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| D | HIS88 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| E | HIS88 |
