1HNO

CRYSTAL STRUCTURE OF PEROXISOMAL DELTA3-DELTA2-ENOYL-COA ISOMERASE FROM SACCHAROMYCES CEREVISIAE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004165	molecular_function	delta(3)-delta(2)-enoyl-CoA isomerase activity
A	0005739	cellular_component	mitochondrion
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 281

Chain	Residue
A	LEU133
A	CYS134
A	LYS168
A	PHE244
A	HOH308
A	HOH309
A	HOH457

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 282

Chain	Residue
A	LYS143
A	PRO202
A	SER203
A	ARG64
A	ASN141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:26527136

Chain	Residue	Details
A	GLU158

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26527136, ECO:0007744|PDB:4ZDB, ECO:0007744|PDB:4ZDC

Chain	Residue	Details
A	SER68

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:26527136, ECO:0007744|PDB:4ZDC

Chain	Residue	Details
A	LEU126

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 499

Chain	Residue	Details
A	ALA70	electrostatic stabiliser
A	ASN101	electrostatic stabiliser, modifies pKa
A	LEU126	electrostatic stabiliser
A	GLU158	proton acceptor, proton donor

---