1HIW

TRIMERIC HIV-1 MATRIX PROTEIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005198	molecular_function	structural molecule activity
B	0005198	molecular_function	structural molecule activity
C	0005198	molecular_function	structural molecule activity
Q	0005198	molecular_function	structural molecule activity
R	0005198	molecular_function	structural molecule activity
S	0005198	molecular_function	structural molecule activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 R 1001

Chain	Residue
A	LYS113
R	ARG22
R	GLY25
R	LYS26
R	LYS27
R	HOH959

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1002

Chain	Residue
A	LYS27
A	HOH936
R	LYS113
A	ARG22
A	GLY25
A	LYS26

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 Q 1003

Chain	Residue
Q	ARG22
Q	LYS26
Q	LYS27
Q	HOH902
S	LYS18

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 R 1004

Chain	Residue
R	VAL35
R	ARG39

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 R 1005

Chain	Residue
R	ARG43

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 S 1006

Chain	Residue
S	ARG22
S	GLY25
S	LYS26
S	LYS27
S	HOH938

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 1007

Chain	Residue
C	ARG22
C	GLY25
C	LYS26
C	LYS27
C	HOH954

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 1008

Chain	Residue
B	GLY25
B	LYS26
B	LYS27

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	Region: {"description":"Interaction with Gp41","evidences":[{"source":"PubMed","id":"8918455","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	210
Details	Region: {"description":"Interaction with host CALM1","evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	42
Details	Region: {"description":"Interaction with host AP3D1","evidences":[{"source":"PubMed","id":"15766529","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	114
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate and RNA","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	24
Details	Region: {"description":"Interaction with membrane phosphatidylinositol 4,5-bisphosphate","evidences":[{"source":"PubMed","id":"16840558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	36
Details	Motif: {"description":"Nuclear export signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---