1HFJ
Asparaginase from Erwinia chrysanthemi, hexagonal form with sulfate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004067 | molecular_function | asparaginase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006528 | biological_process | asparagine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| C | 0004067 | molecular_function | asparaginase activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006528 | biological_process | asparagine metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | GLY14 |
| A | THR15 |
| A | ALA61 |
| A | SER62 |
| A | GLY94 |
| A | THR95 |
| A | ASP96 |
| A | HOH2237 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 400 |
| Chain | Residue |
| C | THR15 |
| C | ALA61 |
| C | SER62 |
| C | GLY94 |
| C | THR95 |
| C | ASP96 |
| C | HOH2053 |
| C | GLY14 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 644 |
| Details | Domain: {"description":"Asparaginase/glutaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"O-isoaspartyl threonine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10099","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10100","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11755201","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8348975","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 3eca |
| Chain | Residue | Details |
| A | THR15 | |
| A | THR95 | |
| A | ASP96 | |
| A | TYR29 | |
| A | LYS168 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 3eca |
| Chain | Residue | Details |
| C | THR15 | |
| C | THR95 | |
| C | ASP96 | |
| C | TYR29 | |
| C | LYS168 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3eca |
| Chain | Residue | Details |
| A | VAL284 | |
| C | THR15 | |
| C | THR95 | |
| C | TYR29 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3eca |
| Chain | Residue | Details |
| A | THR15 | |
| A | THR95 | |
| A | TYR29 | |
| C | VAL284 |
