1HF4
STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 150 |
| Chain | Residue |
| A | SER60 |
| A | CYS64 |
| A | SER72 |
| A | ARG73 |
| A | HOH2058 |
| A | HOH2065 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA B 150 |
| Chain | Residue |
| B | ASN74 |
| B | HOH2069 |
| B | HOH2072 |
| B | HOH2076 |
| B | SER60 |
| B | CYS64 |
| B | ARG73 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 A 801 |
| Chain | Residue |
| A | ASN65 |
| A | ASN74 |
| A | ASN77 |
| A | ILE78 |
| A | PRO79 |
| A | HOH2119 |
| B | ARG112 |
| B | LYS116 |
| B | HOH2109 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 A 802 |
| Chain | Residue |
| A | LYS1 |
| A | GLN41 |
| A | SER86 |
| A | HOH2120 |
| A | HOH2121 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 803 |
| Chain | Residue |
| A | PHE3 |
| A | ALA11 |
| A | ARG14 |
| A | HIS15 |
| A | SER86 |
| A | ASP87 |
| A | ILE88 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 B 801 |
| Chain | Residue |
| A | ARG112 |
| A | LYS116 |
| B | ASN65 |
| B | ASN74 |
| B | ASN77 |
| B | ILE78 |
| B | PRO79 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NO3 B 802 |
| Chain | Residue |
| B | GLY126 |
| B | HOH2126 |
| B | HOH2127 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 B 803 |
| Chain | Residue |
| A | ARG21 |
| A | GLY22 |
| B | ASN65 |
| B | ASP66 |
| B | PRO79 |
| B | CYS80 |
| B | SER81 |
| B | HOH2128 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NO3 B 804 |
| Chain | Residue |
| B | PHE3 |
| B | ALA11 |
| B | ARG14 |
| B | HIS15 |
| B | SER86 |
| B | ASP87 |
| B | ILE88 |
| B | THR89 |
| B | HOH2084 |
| B | HOH2129 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 B 805 |
| Chain | Residue |
| B | ARG45 |
| B | ASN46 |
| B | THR47 |
| B | GLY49 |
| B | HOH2130 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| A | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU35 | |
| A | ASP52 | |
| B | GLU35 | |
| B | ASP52 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP101 | |
| B | ASP101 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 132l |
| Chain | Residue | Details |
| A | GLU35 | |
| A | ASP52 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 132l |
| Chain | Residue | Details |
| B | GLU35 | |
| B | ASP52 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| A | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN46 | |
| A | ASP48 | |
| A | SER50 | |
| A | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| A | ASN59 |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| B | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ASN46 | |
| B | ASP48 | |
| B | SER50 | |
| B | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| B | ASN59 |
