Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004155 | molecular_function | 6,7-dihydropteridine reductase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0051066 | biological_process | dihydrobiopterin metabolic process |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070402 | molecular_function | NADPH binding |
| A | 0070404 | molecular_function | NADH binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD A 244 |
| Chain | Residue |
| A | TYR15 |
| A | LYS72 |
| A | VAL85 |
| A | ALA86 |
| A | GLY87 |
| A | GLY88 |
| A | THR113 |
| A | ALA134 |
| A | TYR149 |
| A | LYS153 |
| A | PRO181 |
| A | GLY16 |
| A | VAL182 |
| A | THR183 |
| A | LEU184 |
| A | ASN189 |
| A | HOH247 |
| A | HOH249 |
| A | HOH252 |
| A | ARG18 |
| A | GLY19 |
| A | ALA20 |
| A | LEU21 |
| A | VAL39 |
| A | ASP40 |
| A | VAL53 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. AkaaldgtpgMigYGMAKGAVhQLCqSLA |
| Chain | Residue | Details |
| A | ALA136-ALA164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | TYR149 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LEU13 | |
| Chain | Residue | Details |
| A | LYS72 | |
| A | LYS78 | |
| A | LYS95 | |
| A | LYS101 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | ASN189 | |
| A | TYR149 | |
| A | LYS153 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | MET146 | |
| A | LYS153 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dhr |
| Chain | Residue | Details |
| A | TYR149 | |
| A | LYS153 | |
