1H9T

FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI IN COMPLEX WITH FADB OPERATOR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000062	molecular_function	fatty-acyl-CoA binding
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0019217	biological_process	regulation of fatty acid metabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0045723	biological_process	positive regulation of fatty acid biosynthetic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000062	molecular_function	fatty-acyl-CoA binding
B	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0019217	biological_process	regulation of fatty acid metabolic process
B	0042803	molecular_function	protein homodimerization activity
B	0045723	biological_process	positive regulation of fatty acid biosynthetic process
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A1241

Chain	Residue
A	GLN53

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A1242

Chain	Residue
A	ARG174

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE AU A1240

Chain	Residue
A	PRO121
A	GLN125
A	CYS200
A	SER201

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE AU B1231

Chain	Residue
B	LEU199
B	CYS200
B	SER201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	136
Details	Domain: {"description":"HTH gntR-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00696","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	70
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PubMed","id":"11279025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11296236","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	30
Details	Region: {"description":"Binds acyl-CoA","evidences":[{"source":"PubMed","id":"7836365","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11296236","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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