1H7S
N-terminal 40kDa fragment of human PMS2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006298 | biological_process | mismatch repair |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0030983 | molecular_function | mismatched DNA binding |
| A | 0032300 | cellular_component | mismatch repair complex |
| A | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006298 | biological_process | mismatch repair |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0030983 | molecular_function | mismatched DNA binding |
| B | 0032300 | cellular_component | mismatch repair complex |
| B | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00058 |
| Number of Residues | 7 |
| Details | DNA_MISMATCH_REPAIR_1 DNA mismatch repair proteins mutL / hexB / PMS1 signature. GFRGEAL |
| Chain | Residue | Details |
| A | GLY105-LEU111 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:7RCI, ECO:0007744|PDB:7RCK |
| Chain | Residue | Details |
| A | ASN45 | |
| B | ASN45 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1EA6, ECO:0007744|PDB:7RCI, ECO:0007744|PDB:7RCK |
| Chain | Residue | Details |
| A | ASP70 | |
| A | LEU111 | |
| B | ASP70 | |
| B | LEU111 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:7RCI |
| Chain | Residue | Details |
| A | GLU109 | |
| B | GLU109 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:7RCK |
| Chain | Residue | Details |
| A | ALA110 | |
| B | ALA110 |
