1H7G

The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, CTP MG2+ complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
A	0009103	biological_process	lipopolysaccharide biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008690	molecular_function	3-deoxy-manno-octulosonate cytidylyltransferase activity
B	0009103	biological_process	lipopolysaccharide biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0033468	biological_process	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B1242

Chain	Residue
B	SER13
B	SER14
B	CTP1243
B	HOH2240
B	HOH2247

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site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE CTP B1243

Chain	Residue
B	HIS73
B	GLU74
B	SER75
B	ARG79
B	GLN96
B	GLY97
B	ASP98
B	MG1242
B	HOH2248
B	HOH2249
B	HOH2250
B	HOH2252
B	HOH2253
B	PRO8
B	ALA9
B	ARG10
B	LYS19

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