1H7G
The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, CTP MG2+ complex
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
A | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
B | 0016779 | molecular_function | nucleotidyltransferase activity |
B | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B1242 |
Chain | Residue |
B | SER13 |
B | SER14 |
B | CTP1243 |
B | HOH2240 |
B | HOH2247 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE CTP B1243 |
Chain | Residue |
B | HIS73 |
B | GLU74 |
B | SER75 |
B | ARG79 |
B | GLN96 |
B | GLY97 |
B | ASP98 |
B | MG1242 |
B | HOH2248 |
B | HOH2249 |
B | HOH2250 |
B | HOH2252 |
B | HOH2253 |
B | PRO8 |
B | ALA9 |
B | ARG10 |
B | LYS19 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1hv9 |
Chain | Residue | Details |
A | ARG15 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1hv9 |
Chain | Residue | Details |
B | ARG15 |