1H7G
The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, CTP MG2+ complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| A | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B1242 |
| Chain | Residue |
| B | SER13 |
| B | SER14 |
| B | CTP1243 |
| B | HOH2240 |
| B | HOH2247 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE CTP B1243 |
| Chain | Residue |
| B | HIS73 |
| B | GLU74 |
| B | SER75 |
| B | ARG79 |
| B | GLN96 |
| B | GLY97 |
| B | ASP98 |
| B | MG1242 |
| B | HOH2248 |
| B | HOH2249 |
| B | HOH2250 |
| B | HOH2252 |
| B | HOH2253 |
| B | PRO8 |
| B | ALA9 |
| B | ARG10 |
| B | LYS19 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| A | ARG15 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| B | ARG15 |
