Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004413 | molecular_function | homoserine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006566 | biological_process | L-threonine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009088 | biological_process | L-threonine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE THR A 401 |
| Chain | Residue |
| A | ALA16 |
| A | GLY260 |
| A | SER261 |
| A | ANP418 |
| A | ASN17 |
| A | PHE22 |
| A | ASP23 |
| A | ASP140 |
| A | ASN141 |
| A | THR183 |
| A | ARG187 |
| A | ARG235 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE ANP A 418 |
| Chain | Residue |
| A | ILE55 |
| A | PRO56 |
| A | LYS61 |
| A | ASN62 |
| A | VAL63 |
| A | LYS87 |
| A | ALA91 |
| A | GLY92 |
| A | GLY94 |
| A | LEU95 |
| A | GLY96 |
| A | SER97 |
| A | SER98 |
| A | SER101 |
| A | THR183 |
| A | SER261 |
| A | THR401 |
| A | HOH2247 |
| A | HOH2248 |
| A | HOH2249 |
Functional Information from PROSITE/UniProt
| site_id | PS00627 |
| Number of Residues | 12 |
| Details | GHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. VKaGsGLGSSAA |
| Chain | Residue | Details |
| A | VAL89-ALA100 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fwk |
| Chain | Residue | Details |
| A | THR183 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 778 |
| Chain | Residue | Details |
| A | GLU130 | metal ligand |
| A | THR183 | electrostatic stabiliser, polar interaction |
