1H0M

Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0009372	biological_process	quorum sensing
A	0032993	cellular_component	protein-DNA complex
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0003677	molecular_function	DNA binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0009372	biological_process	quorum sensing
B	0032993	cellular_component	protein-DNA complex
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0001216	molecular_function	DNA-binding transcription activator activity
C	0003677	molecular_function	DNA binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0009372	biological_process	quorum sensing
C	0032993	cellular_component	protein-DNA complex
C	0045893	biological_process	positive regulation of DNA-templated transcription
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0001216	molecular_function	DNA-binding transcription activator activity
D	0003677	molecular_function	DNA binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0009372	biological_process	quorum sensing
D	0032993	cellular_component	protein-DNA complex
D	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE HSL A1235

Chain	Residue
A	TRP57
A	TYR61
A	ASP70
A	VAL72
A	PHE101
A	TYR102
A	ALA105
A	ILE110

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OOA A1236

Chain	Residue
A	TYR53
A	GLN58
A	TYR61
A	ASP70
A	VAL72
A	MSE127
A	LEU40

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HSL B1235

Chain	Residue
B	TRP57
B	TYR61
B	ASP70
B	VAL72
B	TRP85
B	PHE101
B	TYR102
B	ALA105
B	ILE110

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OOA B1236

Chain	Residue
B	LEU40
B	TYR53
B	GLN58
B	TYR61
B	PHE62
B	ASP70
B	THR129

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE HSL C1235

Chain	Residue
C	TYR53
C	TRP57
C	ASP70
C	VAL72
C	PHE101
C	ALA105
C	ILE110
A	HOH2002

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OOA C1236

Chain	Residue
C	LEU40
C	TYR53
C	TYR61
C	VAL72
C	TRP85
C	MSE127
C	THR129

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE HSL D1235

Chain	Residue
D	TRP57
D	TYR61
D	ASP70
D	VAL72
D	TRP85
D	ALA105
D	ILE110
A	HOH2004

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OOA D1236

Chain	Residue
D	ALA38
D	LEU40
D	TYR53
D	TYR61
D	TRP85
D	THR129
A	HOH2003

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