1H0M
Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0001216 | molecular_function | DNA-binding transcription activator activity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0032993 | cellular_component | protein-DNA complex |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0001216 | molecular_function | DNA-binding transcription activator activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0032993 | cellular_component | protein-DNA complex |
| B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| C | 0000976 | molecular_function | transcription cis-regulatory region binding |
| C | 0001216 | molecular_function | DNA-binding transcription activator activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0032993 | cellular_component | protein-DNA complex |
| C | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| D | 0000976 | molecular_function | transcription cis-regulatory region binding |
| D | 0001216 | molecular_function | DNA-binding transcription activator activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0032993 | cellular_component | protein-DNA complex |
| D | 0045893 | biological_process | positive regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HSL A1235 |
| Chain | Residue |
| A | TRP57 |
| A | TYR61 |
| A | ASP70 |
| A | VAL72 |
| A | PHE101 |
| A | TYR102 |
| A | ALA105 |
| A | ILE110 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OOA A1236 |
| Chain | Residue |
| A | TYR53 |
| A | GLN58 |
| A | TYR61 |
| A | ASP70 |
| A | VAL72 |
| A | MSE127 |
| A | LEU40 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HSL B1235 |
| Chain | Residue |
| B | TRP57 |
| B | TYR61 |
| B | ASP70 |
| B | VAL72 |
| B | TRP85 |
| B | PHE101 |
| B | TYR102 |
| B | ALA105 |
| B | ILE110 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OOA B1236 |
| Chain | Residue |
| B | LEU40 |
| B | TYR53 |
| B | GLN58 |
| B | TYR61 |
| B | PHE62 |
| B | ASP70 |
| B | THR129 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HSL C1235 |
| Chain | Residue |
| C | TYR53 |
| C | TRP57 |
| C | ASP70 |
| C | VAL72 |
| C | PHE101 |
| C | ALA105 |
| C | ILE110 |
| A | HOH2002 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OOA C1236 |
| Chain | Residue |
| C | LEU40 |
| C | TYR53 |
| C | TYR61 |
| C | VAL72 |
| C | TRP85 |
| C | MSE127 |
| C | THR129 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HSL D1235 |
| Chain | Residue |
| D | TRP57 |
| D | TYR61 |
| D | ASP70 |
| D | VAL72 |
| D | TRP85 |
| D | ALA105 |
| D | ILE110 |
| A | HOH2004 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE OOA D1236 |
| Chain | Residue |
| D | ALA38 |
| D | LEU40 |
| D | TYR53 |
| D | TYR61 |
| D | TRP85 |
| D | THR129 |
| A | HOH2003 |
