1GWS

hexadecaheme high molecular weight cytochrome Hmc from Desulfovibrio vulgaris Hildenborough

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009055	molecular_function	electron transfer activity
A	0020037	molecular_function	heme binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM A 602

Chain	Residue
A	PHE33
A	LEU90
A	LYS96
A	GLY98
A	PRO99
A	HOH2141
A	ARG34
A	GLN37
A	HIS38
A	PHE64
A	ASN82
A	CYS83
A	CYS86
A	HIS87

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM A 604

Chain	Residue
A	GLY122
A	PHE123
A	HIS128
A	HIS131
A	ASN146
A	CYS147
A	CYS150
A	HIS151
A	GLU168
A	SER170
A	ARG172
A	LEU234
A	ARG236
A	ASP276
A	CYS277
A	ARG278
A	ILE285
A	HEC606

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM A 607

Chain	Residue
A	HIS35
A	TRP118
A	GLU120
A	ILE121
A	ARG172
A	LEU186
A	ALA190
A	HIS191
A	HIS198
A	PRO210
A	VAL211
A	ASN212
A	CYS213
A	CYS216
A	HIS217
A	HEC601

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM A 608

Chain	Residue
A	GLN238
A	PHE265
A	HIS267
A	ALA274
A	ASP276
A	CYS277
A	CYS280
A	HIS281
A	ILE285
A	ASP286
A	THR287
A	CYS288
A	HEC610
A	HOH2146
A	HOH2147

---

site_id	AC5
Number of Residues	13
Details	BINDING SITE FOR RESIDUE HEC A 601

Chain	Residue
A	PHE33
A	HIS35
A	CYS49
A	CYS52
A	HIS53
A	LEU62
A	LYS63
A	PHE64
A	ARG66
A	TYR79
A	HIS191
A	HEC607
A	HOH2140

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 603

Chain	Residue
A	ILE17
A	GLY18
A	ALA19
A	MET20
A	LEU26
A	ASP27
A	LEU28
A	TYR79
A	HIS80
A	GLN100
A	ASP101
A	CYS104
A	CYS107
A	HIS108

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE HEC A 605

Chain	Residue
A	HOH2142
A	LYS59
A	HIS152
A	TYR154
A	SER170
A	CYS171
A	CYS174
A	HIS175
A	LYS182
A	ALA193

---

site_id	AC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC A 606

Chain	Residue
A	PHE123
A	ARG130
A	HIS131
A	CYS150
A	CYS194
A	CYS197
A	HIS198
A	GLU207
A	THR208
A	GLY209
A	PRO210
A	PHE225
A	HEC604
A	HOH2143
A	HOH2144

---

site_id	AC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 609

Chain	Residue
A	CYS280
A	HIS282
A	ARG284
A	THR287
A	CYS288
A	CYS291
A	HIS292
A	ASP299
A	SER300
A	LYS301
A	ALA308
A	GLN311
A	SER314
A	ARG316

---

site_id	BC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC A 610

Chain	Residue
A	PHE265
A	ASP266
A	HIS270
A	LYS273
A	MET315
A	ARG316
A	SER317
A	CYS318
A	CYS321
A	HIS322
A	ARG386
A	LYS433
A	LEU434
A	THR437
A	HEC608
A	HEC612
A	HOH2071

---

site_id	BC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 611

Chain	Residue
A	CYS331
A	CYS334
A	HIS335
A	PRO340
A	THR341
A	GLN346
A	ASP432
A	PHE438
A	HIS439
A	THR444
A	LEU445
A	GLN447
A	HOH2149
A	HOH2151

---

site_id	BC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEC A 612

Chain	Residue
A	GLU230
A	ILE244
A	LEU245
A	PRO246
A	THR259
A	MET260
A	LYS261
A	PRO262
A	VAL263
A	LEU305
A	GLU306
A	MET309
A	HIS310
A	CYS347
A	CYS350
A	HIS351
A	HEC610

---

site_id	BC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEC A 613

Chain	Residue
A	ILE398
A	PHE416
A	HIS418
A	VAL422
A	CYS446
A	CYS449
A	HIS450
A	SER456
A	LEU457
A	PRO459
A	LYS461
A	CYS462
A	TYR484
A	HEC615
A	HOH2131

---

site_id	BC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEC A 614

Chain	Residue
A	PHE337
A	LYS339
A	CYS449
A	HIS451
A	ASN452
A	CYS462
A	SER464
A	CYS465
A	HIS466
A	ARG477
A	PRO478
A	ALA483
A	GLN486
A	GLN487

---

site_id	BC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEC A 615

Chain	Residue
A	ILE404
A	SER414
A	PHE416
A	LYS420
A	ILE421
A	GLN487
A	CYS488
A	CYS491
A	HIS492
A	PRO500
A	HEC613

---

site_id	BC7
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEC A 616

Chain	Residue
A	THR88
A	GLN100
A	ILE404
A	GLY405
A	SER406
A	ILE407
A	ALA408
A	LYS409
A	GLU410
A	TYR411
A	LYS481
A	TYR484
A	HIS485
A	CYS488
A	ASN502
A	CYS505
A	CYS508
A	HIS509

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	31
Details	BINDING: axial binding residue

Chain	Residue	Details
A	HIS35
A	HIS152
A	HIS175
A	HIS191
A	HIS198
A	HIS217
A	HIS267
A	HIS270
A	HIS281
A	HIS282
A	HIS292
A	HIS38
A	HIS310
A	HIS322
A	HIS335
A	HIS351
A	HIS418
A	HIS439
A	HIS450
A	HIS451
A	HIS466
A	HIS485
A	HIS53
A	HIS492
A	HIS509
A	HIS80
A	HIS87
A	HIS108
A	HIS128
A	HIS131
A	HIS151

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	BINDING: covalent

Chain	Residue	Details
A	CYS49
A	CYS174
A	CYS194
A	CYS197
A	CYS213
A	CYS216
A	CYS277
A	CYS280
A	CYS288
A	CYS291
A	CYS318
A	CYS52
A	CYS321
A	CYS331
A	CYS334
A	CYS347
A	CYS350
A	CYS446
A	CYS449
A	CYS462
A	CYS465
A	CYS488
A	CYS83
A	CYS491
A	CYS505
A	CYS508
A	CYS86
A	CYS104
A	CYS107
A	CYS147
A	CYS150
A	CYS171

---