Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 501 |
Chain | Residue |
A | SER113 |
A | SER114 |
A | THR322 |
A | HOH2175 |
A | HOH2389 |
A | HOH2390 |
A | HOH2391 |
A | HOH2392 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 502 |
Chain | Residue |
A | SER245 |
A | SER246 |
A | SER247 |
A | HOH2393 |
A | HOH2394 |
A | LYS243 |
site_id | AC3 |
Number of Residues | 20 |
Details | BINDING SITE FOR CHAIN I OF INHIBITOR H256 |
Chain | Residue |
A | ASP15 |
A | ASP33 |
A | ASP35 |
A | GLY37 |
A | SER78 |
A | TYR79 |
A | GLY80 |
A | ASP81 |
A | SER83 |
A | LEU133 |
A | ASP219 |
A | GLY221 |
A | THR222 |
A | THR223 |
A | HOH2060 |
A | HOH2372 |
I | HOH2001 |
I | HOH2002 |
I | HOH2003 |
I | HOH2004 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
Chain | Residue | Details |
A | LEU32-VAL43 | |
A | ILE217-PRO228 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | ASP35 | |
A | THR200 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | ASP35 | |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | ASP219 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | SER38 | |
A | ASP35 | |
A | THR222 | |
A | ASP219 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | ASP35 | |
A | THR220 | |
A | ASP219 | |
A | THR36 | |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | SER38 | |
A | ASP35 | |
A | ASP219 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1am5 |
Chain | Residue | Details |
A | ASP35 | |
A | THR222 | |
A | ASP219 | |
A | THR36 | |