Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| A | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| B | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1390 |
| Chain | Residue |
| A | GLN33 |
| A | HIS34 |
| A | LYS85 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1391 |
| Chain | Residue |
| A | ARG285 |
| A | PRO307 |
| A | SER309 |
| A | HOH2281 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1392 |
| Chain | Residue |
| A | GLU252 |
| A | SER250 |
| A | ARG251 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4003 |
| Chain | Residue |
| A | HOH2287 |
| B | GLN33 |
| B | HIS34 |
| B | LYS85 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4004 |
| Chain | Residue |
| A | LYS145 |
| A | GLN151 |
| A | ASN155 |
| A | HOH2131 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1389 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1390 |
| Chain | Residue |
| B | ARG222 |
| B | LYS378 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1391 |
| Chain | Residue |
| B | ARG224 |
| B | ASN226 |
| B | VAL230 |
| site_id | AC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NDP A 1393 |
| Chain | Residue |
| A | PRO69 |
| A | VAL171 |
| A | ASN172 |
| A | THR175 |
| A | THR199 |
| A | SER200 |
| A | ALA201 |
| A | VAL202 |
| A | ARG222 |
| A | ARG224 |
| A | VAL275 |
| A | TYR296 |
| A | GLY297 |
| A | GLY298 |
| A | MET299 |
| A | PHE321 |
| A | TRP322 |
| A | VAL323 |
| A | LYS381 |
| A | GOL1387 |
| A | HOH2282 |
| A | HOH2283 |
| A | HOH2284 |
| A | HOH2285 |
| A | HOH2286 |
| site_id | BC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NDP B 1392 |
| Chain | Residue |
| B | PRO69 |
| B | VAL171 |
| B | ASN172 |
| B | THR175 |
| B | THR199 |
| B | SER200 |
| B | ALA201 |
| B | VAL202 |
| B | ARG222 |
| B | ARG224 |
| B | VAL275 |
| B | TYR296 |
| B | GLY297 |
| B | GLY298 |
| B | MET299 |
| B | PHE321 |
| B | TRP322 |
| B | VAL323 |
| B | LYS381 |
| B | HOH2036 |
| B | HOH2187 |
| B | HOH2294 |
| B | HOH2301 |
| B | HOH2302 |
| B | HOH2303 |
| B | HOH2304 |
| B | HOH2305 |
| B | HOH2306 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1387 |
| Chain | Residue |
| A | SER70 |
| A | ASN73 |
| A | TYR79 |
| A | TYR296 |
| A | GLY297 |
| A | NDP1393 |
| A | HOH2051 |
| B | ILE312 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1388 |
| Chain | Residue |
| A | VAL242 |
| A | THR244 |
| A | GLN247 |
| A | HOH2183 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1389 |
| Chain | Residue |
| A | ASN248 |
| A | ASN249 |
| A | SER250 |
| A | ARG251 |
| A | GLY254 |
| A | ARG285 |
| A | LYS286 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 1387 |
| Chain | Residue |
| B | TYR183 |
| B | GLY320 |
| B | PHE321 |
| B | TRP322 |
| B | GLU325 |
| B | HOH2149 |
| B | HOH2299 |
| A | TYR311 |
| A | ILE312 |
| A | ASN315 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1388 |
| Chain | Residue |
| B | LEU227 |
| B | VAL242 |
| B | THR244 |
| B | GLN247 |
| B | HOH2300 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TYR79 | |
| B | TYR79 | |
| Chain | Residue | Details |
| A | ASN172 | |
| B | TYR296 | |
| B | PHE321 | |
| B | LYS381 | |
| A | THR199 | |
| A | ARG222 | |
| A | TYR296 | |
| A | PHE321 | |
| A | LYS381 | |
| B | ASN172 | |
| B | THR199 | |
| B | ARG222 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12614607, 10521269 |
| Chain | Residue | Details |
| A | TYR79 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 12614607, 10521269 |
| Chain | Residue | Details |
| B | TYR79 | |
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| A | TYR79 | electrostatic stabiliser, increase electrophilicity |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| B | TYR79 | electrostatic stabiliser, increase electrophilicity |
