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1GT6

S146A mutant of Thermomyces (Humicola) lanuginosa lipase complex with oleic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0004806molecular_functiontriacylglycerol lipase activity
A0006629biological_processlipid metabolic process
A0016042biological_processlipid catabolic process
A0016787molecular_functionhydrolase activity
B0004806molecular_functiontriacylglycerol lipase activity
B0006629biological_processlipid metabolic process
B0016042biological_processlipid catabolic process
B0016787molecular_functionhydrolase activity
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE OLA A1270
ChainResidue
AGLY82
ASER83
AASN92
AHIS145
AALA146
ALEU147
AVAL203
AHIS258

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE OLA B1270
ChainResidue
BSER83
BASN92
BHIS110
BALA146
BVAL203
BHIS258
BTYR21

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"8014587","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsActive site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"8014587","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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