1GSQ

THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005737	cellular_component	cytoplasm
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE GDN A 203

Chain	Residue
A	GLN62
A	SER63
A	ASP96
A	VAL102
A	PHE106
A	HOH302
A	HOH359
A	HOH382
A	TYR7
A	PHE8
A	ARG13
A	TRP38
A	LYS42
A	ASN48
A	MET50
A	PRO51

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site_id	GDB
Number of Residues	1
Details

Chain	Residue
A	GDN203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	77
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	122
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8710848","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7727393","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"8710848","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1oe8

Chain	Residue	Details
A	TYR7

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