1GQC
THE STRUCTURE OF CMP:2-KETO-3-DEOXY-MANNO-OCTONIC ACID SYNTHETASE COMPLEXED WITH CMP-Kdo at 100K
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
| A | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| A | 0044281 | biological_process | small molecule metabolic process |
| A | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008690 | molecular_function | 3-deoxy-manno-octulosonate cytidylyltransferase activity |
| B | 0009103 | biological_process | lipopolysaccharide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0033468 | biological_process | CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process |
| B | 0044281 | biological_process | small molecule metabolic process |
| B | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1243 |
| Chain | Residue |
| A | GLN96 |
| A | ASP98 |
| A | GLU99 |
| A | CMK1244 |
| A | HOH2109 |
| A | HOH2115 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B1242 |
| Chain | Residue |
| B | HOH2148 |
| B | ASP98 |
| B | ASP225 |
| B | C5P1243 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE CMK A1244 |
| Chain | Residue |
| A | PRO8 |
| A | ARG10 |
| A | HIS73 |
| A | GLU74 |
| A | GLY76 |
| A | ARG79 |
| A | GLN96 |
| A | GLY97 |
| A | ASP98 |
| A | VAL140 |
| A | ARG155 |
| A | HIS172 |
| A | GLY174 |
| A | TYR176 |
| A | LEU200 |
| A | GLU201 |
| A | GLN202 |
| A | MG1243 |
| A | HOH2111 |
| A | HOH2112 |
| A | HOH2113 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE C5P B1243 |
| Chain | Residue |
| B | PRO8 |
| B | ALA9 |
| B | ARG10 |
| B | LYS19 |
| B | HIS73 |
| B | GLU74 |
| B | SER75 |
| B | GLY76 |
| B | ARG79 |
| B | GLN96 |
| B | GLY97 |
| B | ASP98 |
| B | MG1242 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| A | ARG15 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1hv9 |
| Chain | Residue | Details |
| B | ARG15 |
