Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0006782 | biological_process | protoporphyrinogen IX biosynthetic process |
| A | 0006783 | biological_process | heme biosynthetic process |
| A | 0008883 | molecular_function | glutamyl-tRNA reductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019353 | biological_process | protoporphyrinogen IX biosynthetic process from glutamate |
| A | 0033014 | biological_process | tetrapyrrole biosynthetic process |
| A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GMC A1405 |
| Chain | Residue |
| A | ARG23 |
| A | GLU25 |
| A | SER48 |
| A | GLU101 |
| A | GLU1406 |
| A | HOH2346 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GLU A1406 |
| Chain | Residue |
| A | SER94 |
| A | GLU99 |
| A | GLU101 |
| A | ILE102 |
| A | GLN105 |
| A | GMC1405 |
| A | HOH2055 |
| A | HOH2347 |
| A | THR47 |
| A | ASN49 |
| A | ARG50 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CIT A1407 |
| Chain | Residue |
| A | GLU99 |
| A | GLN100 |
| A | ALA147 |
| A | VAL148 |
| A | SER149 |
| A | SER152 |
| A | ARG300 |
| A | HOH2349 |
| A | HOH2350 |
| A | HOH2352 |
| A | HOH2353 |
| A | HOH2354 |
Functional Information from PROSITE/UniProt
| site_id | PS00747 |
| Number of Residues | 24 |
| Details | GLUTR Glutamyl-tRNA reductase signature. HLfrVASGLESmMVGEqEILRQVK |
| Chain | Residue | Details |
| A | HIS84-LYS107 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for activity"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | a catalytic site defined by CSA, PubMed 10521455 |
| Chain | Residue | Details |
| A | SER48 | |
| A | HIS84 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 804 |
| Chain | Residue | Details |
| A | SER48 | covalently attached, nucleofuge, nucleophile |
| A | HIS84 | electrostatic stabiliser |
