1GOA

COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004523	molecular_function	RNA-DNA hybrid ribonuclease activity

Functional Information from PDB Data

site_id	MG
Number of Residues	3
Details

Chain	Residue
A	ASP10
A	GLU48
A	ASP70

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"1311386","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	6
Details	M-CSA 163

Chain	Residue	Details
A	ASP10	metal ligand
A	GLY11	metal ligand
A	GLU48	increase acidity, increase basicity, unknown
A	ASP70	metal ligand
A	HIS124	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, unknown
A	ASP134	increase acidity, metal ligand, proton acceptor, proton donor

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