1GNE

THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GSH A 233

Chain	Residue
A	TYR6
A	SER67
A	ASP100
A	HOH235
A	HOH243
A	HOH284
A	HOH289
A	HOH293
A	HOH333
A	HOH341
A	HOH348
A	TRP7
A	LEU12
A	TRP40
A	LYS44
A	ASN53
A	LEU54
A	PRO55
A	GLN66

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	81
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	118
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"7538846","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12596270","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1oe8

Chain	Residue	Details
A	TYR6

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