1GN2

S123C mutant of the iron-superoxide dismutase from Mycobacterium tuberculosis.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004784	molecular_function	superoxide dismutase activity
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006801	biological_process	superoxide metabolic process
A	0006979	biological_process	response to oxidative stress
A	0016491	molecular_function	oxidoreductase activity
A	0019430	biological_process	removal of superoxide radicals
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
A	0098754	biological_process	detoxification
B	0004784	molecular_function	superoxide dismutase activity
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006801	biological_process	superoxide metabolic process
B	0006979	biological_process	response to oxidative stress
B	0016491	molecular_function	oxidoreductase activity
B	0019430	biological_process	removal of superoxide radicals
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
B	0098754	biological_process	detoxification
C	0004784	molecular_function	superoxide dismutase activity
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006801	biological_process	superoxide metabolic process
C	0006979	biological_process	response to oxidative stress
C	0016491	molecular_function	oxidoreductase activity
C	0019430	biological_process	removal of superoxide radicals
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
C	0098754	biological_process	detoxification
D	0004784	molecular_function	superoxide dismutase activity
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006801	biological_process	superoxide metabolic process
D	0006979	biological_process	response to oxidative stress
D	0016491	molecular_function	oxidoreductase activity
D	0019430	biological_process	removal of superoxide radicals
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding
D	0098754	biological_process	detoxification
E	0004784	molecular_function	superoxide dismutase activity
E	0005506	molecular_function	iron ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006801	biological_process	superoxide metabolic process
E	0006979	biological_process	response to oxidative stress
E	0016491	molecular_function	oxidoreductase activity
E	0019430	biological_process	removal of superoxide radicals
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding
E	0098754	biological_process	detoxification
F	0004784	molecular_function	superoxide dismutase activity
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006801	biological_process	superoxide metabolic process
F	0006979	biological_process	response to oxidative stress
F	0016491	molecular_function	oxidoreductase activity
F	0019430	biological_process	removal of superoxide radicals
F	0042597	cellular_component	periplasmic space
F	0046872	molecular_function	metal ion binding
F	0098754	biological_process	detoxification
G	0004784	molecular_function	superoxide dismutase activity
G	0005506	molecular_function	iron ion binding
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006801	biological_process	superoxide metabolic process
G	0006979	biological_process	response to oxidative stress
G	0016491	molecular_function	oxidoreductase activity
G	0019430	biological_process	removal of superoxide radicals
G	0042597	cellular_component	periplasmic space
G	0046872	molecular_function	metal ion binding
G	0098754	biological_process	detoxification
H	0004784	molecular_function	superoxide dismutase activity
H	0005506	molecular_function	iron ion binding
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006801	biological_process	superoxide metabolic process
H	0006979	biological_process	response to oxidative stress
H	0016491	molecular_function	oxidoreductase activity
H	0019430	biological_process	removal of superoxide radicals
H	0042597	cellular_component	periplasmic space
H	0046872	molecular_function	metal ion binding
H	0098754	biological_process	detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 999

Chain	Residue
A	HIS28
A	HIS76
A	ASP160
A	HIS164

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE B 999

Chain	Residue
B	HIS28
B	HIS76
B	ASP160
B	HIS164

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 999

Chain	Residue
C	HIS76
C	ASP160
C	HIS164
C	HIS28

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 999

Chain	Residue
D	HIS28
D	HIS76
D	ASP160
D	HIS164

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE E 999

Chain	Residue
E	HIS28
E	HIS76
E	ASP160
E	HIS164

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE F 999

Chain	Residue
F	HIS28
F	HIS76
F	ASP160
F	HIS164

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE G 999

Chain	Residue
G	HIS28
G	HIS76
G	ASP160
G	HIS164

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE H 999

Chain	Residue
H	HIS28
H	HIS76
H	ASP160
H	HIS164

---

Functional Information from PROSITE/UniProt

site_id	PS00088
Number of Residues	8
Details	SOD_MN Manganese and iron superoxide dismutases signature. DmWEHAFY

Chain	Residue	Details
A	ASP160-TYR167

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11747311","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7877174","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8674528","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9490054","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GN2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GN3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GN6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IDS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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