Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE APD A 501 |
| Chain | Residue |
| A | CYS29 |
| A | AEM500 |
| A | DFA502 |
| B | GLU245 |
| B | DFA502 |
| A | TRP30 |
| A | GLY73 |
| A | GLY74 |
| A | PRO76 |
| A | ALA173 |
| A | GLY198 |
| A | HIS199 |
| A | GLU245 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DFA A 502 |
| Chain | Residue |
| A | ASP69 |
| A | ASN72 |
| A | GLY73 |
| A | GLY74 |
| A | TYR75 |
| A | APD501 |
| A | HOH2181 |
| B | MET195 |
| B | GLY198 |
| B | APD501 |
| B | DFA502 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AEM B 500 |
| Chain | Residue |
| B | GLN23 |
| B | GLY27 |
| B | CYS29 |
| B | GLY198 |
| B | APD501 |
| B | HOH2106 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DFA B 502 |
| Chain | Residue |
| A | SER175 |
| A | GLY198 |
| A | APD501 |
| A | DFA502 |
| B | ASP69 |
| B | ASN72 |
| B | GLY73 |
| B | GLY74 |
| B | TYR75 |
| B | APD501 |
| B | HOH2170 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AEM C 500 |
| Chain | Residue |
| C | GLN23 |
| C | GLY27 |
| C | SER28 |
| C | CYS29 |
| C | GLY198 |
| C | APD501 |
| C | HOH2213 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE APD C 501 |
| Chain | Residue |
| C | CYS29 |
| C | TRP30 |
| C | GLY73 |
| C | GLY74 |
| C | PRO76 |
| C | ALA173 |
| C | GLY198 |
| C | HIS199 |
| C | AEM500 |
| C | DFA502 |
| C | HOH2148 |
| C | HOH2150 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AEM A 500 |
| Chain | Residue |
| A | GLN23 |
| A | GLY27 |
| A | CYS29 |
| A | GLY198 |
| A | APD501 |
| A | HOH2212 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE APD B 501 |
| Chain | Residue |
| A | GLU245 |
| A | DFA502 |
| B | CYS29 |
| B | TRP30 |
| B | GLY73 |
| B | GLY74 |
| B | PRO76 |
| B | ALA173 |
| B | GLY198 |
| B | HIS199 |
| B | AEM500 |
| B | DFA502 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DFA C 502 |
| Chain | Residue |
| C | ASN72 |
| C | GLY73 |
| C | GLY74 |
| C | TYR75 |
| C | APD501 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGSCWAfGA |
| Chain | Residue | Details |
| A | GLN23-ALA34 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAIRILGWG |
| Chain | Residue | Details |
| A | GLY197-GLY207 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvANSWntdWGdnGFFkI |
| Chain | Residue | Details |
| A | TYR214-ILE233 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"9299326","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P10605","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"3463996","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS199 | |
| A | ASN219 | |
| A | CYS29 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS199 | |
| B | ASN219 | |
| B | CYS29 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | HIS199 | |
| C | ASN219 | |
| C | CYS29 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS199 | |
| A | GLN23 | |
| A | CYS29 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS199 | |
| B | GLN23 | |
| B | CYS29 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | HIS199 | |
| C | GLN23 | |
| C | CYS29 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS199 | |
| A | ASN219 | |
| A | GLN23 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS199 | |
| B | ASN219 | |
| B | GLN23 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| C | HIS199 | |
| C | ASN219 | |
| C | GLN23 | |
