1GLJ

ESCHERICHIA COLI GLYCEROL KINASE MUTANT WITH BOUND ATP ANALOG SHOWING SUBSTANTIAL DOMAIN MOTION

Functional Information from GO Data

Chain	GOid	namespace	contents
O	0000166	molecular_function	nucleotide binding
O	0003824	molecular_function	catalytic activity
O	0004370	molecular_function	glycerol kinase activity
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005829	cellular_component	cytosol
O	0005975	biological_process	carbohydrate metabolic process
O	0006071	biological_process	glycerol metabolic process
O	0006072	biological_process	glycerol-3-phosphate metabolic process
O	0006974	biological_process	DNA damage response
O	0008270	molecular_function	zinc ion binding
O	0016301	molecular_function	kinase activity
O	0016740	molecular_function	transferase activity
O	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
O	0019563	biological_process	glycerol catabolic process
O	0042802	molecular_function	identical protein binding
O	0046872	molecular_function	metal ion binding
Y	0000166	molecular_function	nucleotide binding
Y	0003824	molecular_function	catalytic activity
Y	0004370	molecular_function	glycerol kinase activity
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005829	cellular_component	cytosol
Y	0005975	biological_process	carbohydrate metabolic process
Y	0006071	biological_process	glycerol metabolic process
Y	0006072	biological_process	glycerol-3-phosphate metabolic process
Y	0006974	biological_process	DNA damage response
Y	0008270	molecular_function	zinc ion binding
Y	0016301	molecular_function	kinase activity
Y	0016740	molecular_function	transferase activity
Y	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
Y	0019563	biological_process	glycerol catabolic process
Y	0042802	molecular_function	identical protein binding
Y	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	PUTATIVE PROTON ACCEPTOR FROM NUCLEOPHILIC O3 POSITION OF GLYCEROL, CHAIN Y.

Chain	Residue
O	ASP245

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site_id	AC2
Number of Residues	1
Details	PUTATIVE PROTON ACCEPTOR FROM NUCLEOPHILIC O3 POSITION OF GLYCEROL, CHAIN O.

Chain	Residue
Y	ASP245

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG Y 602

Chain	Residue
Y	ASP10
Y	ASP245
Y	ATS601

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site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ATS Y 601

Chain	Residue
Y	GLY266
Y	THR267
Y	GLY310
Y	ALA311
Y	GLN314
Y	SER329
Y	GLY411
Y	ALA412
Y	ASN415
Y	MG602
Y	GLY12
Y	THR13
Y	THR14
Y	SER15

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ATS O 601

Chain	Residue
O	THR13
O	THR14
O	GLY266
O	THR267
O	GLY310
O	ALA311
O	GLN314
O	ALA326
O	GLY411
O	ALA412
O	ASN415

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL Y 600

Chain	Residue
Y	GLN82
Y	ARG83
Y	GLU84
Y	TRP103
Y	TYR135
Y	ASP245
Y	GLN246
Y	PHE270

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL O 600

Chain	Residue
O	THR13
O	ARG83
O	GLU84
O	TRP103
O	TYR135
O	ASP245
O	GLN246
O	PHE270

---

Functional Information from PROSITE/UniProt

site_id	PS00445
Number of Residues	21
Details	FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GaIFGLtrgvnan.HIIRATLE

Chain	Residue	Details
Y	GLY362-GLU382

---

site_id	PS00933
Number of Residues	13
Details	FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. YfSgtKVKWILDH

Chain	Residue	Details
Y	TYR135-HIS147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8170944","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GLC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10090737","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1BWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10090737","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1GLJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8170944","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8430315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9817843","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GLB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9843423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8430315","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9843423","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BO5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BOT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10090737","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1BWF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8170944","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8430315","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GLB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GLE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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