Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1GL9

Archaeoglobus fulgidus reverse gyrase complexed with ADPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0003689	molecular_function	DNA clamp loader activity
B	0003916	molecular_function	DNA topoisomerase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006265	biological_process	DNA topological change
B	0006268	biological_process	DNA unwinding involved in DNA replication
B	0006338	biological_process	chromatin remodeling
B	0008094	molecular_function	ATP-dependent activity, acting on DNA
B	0008270	molecular_function	zinc ion binding
B	0009378	molecular_function	four-way junction helicase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0034335	molecular_function	DNA negative supercoiling activity
B	0036121	molecular_function	double-stranded DNA helicase activity
B	0046872	molecular_function	metal ion binding
B	0061749	molecular_function	forked DNA-dependent helicase activity
B	0061775	molecular_function	cohesin loader activity
B	0140584	molecular_function	chromatin extrusion motor activity
B	0140588	biological_process	chromatin looping
B	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
B	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
B	0160097	molecular_function	reverse gyrase activity
B	1990518	molecular_function	single-stranded 3'-5' DNA helicase activity
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0003689	molecular_function	DNA clamp loader activity
C	0003916	molecular_function	DNA topoisomerase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006265	biological_process	DNA topological change
C	0006268	biological_process	DNA unwinding involved in DNA replication
C	0006338	biological_process	chromatin remodeling
C	0008094	molecular_function	ATP-dependent activity, acting on DNA
C	0008270	molecular_function	zinc ion binding
C	0009378	molecular_function	four-way junction helicase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0034335	molecular_function	DNA negative supercoiling activity
C	0036121	molecular_function	double-stranded DNA helicase activity
C	0046872	molecular_function	metal ion binding
C	0061749	molecular_function	forked DNA-dependent helicase activity
C	0061775	molecular_function	cohesin loader activity
C	0140584	molecular_function	chromatin extrusion motor activity
C	0140588	biological_process	chromatin looping
C	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
C	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity
C	0160097	molecular_function	reverse gyrase activity
C	1990518	molecular_function	single-stranded 3'-5' DNA helicase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B2056

Chain	Residue
B	THR85
B	ASP182

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C2056

Chain	Residue
C	THR85

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ANP B2055

Chain	Residue
B	VAL82
B	GLY83
B	LYS84
B	THR85
B	SER86
B	ARG498
B	GLN499
B	PHE50
B	VAL54
B	GLU56
B	ARG58
B	GLN61
B	GLY81

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ANP C2055

Chain	Residue
C	PHE50
C	VAL54
C	GLU56
C	GLN61
C	GLY81
C	VAL82
C	GLY83
C	LYS84
C	THR85
C	SER86
C	ARG498
C	GLN499

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	ZN_FING: RG N-terminal-type => ECO:0000255\|PROSITE-ProRule:PRU01380

Chain	Residue	Details
B	MET1-LEU43
C	MET1-LEU43

site_id	SWS_FT_FI2
Number of Residues	56
Details	ZN_FING: RG C-terminal-type => ECO:0000255\|PROSITE-ProRule:PRU01381

Chain	Residue	Details
B	ILE581-SER609
C	ILE581-SER609

site_id	SWS_FT_FI3
Number of Residues	2
Details	ACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255\|PROSITE-ProRule:PRU01383

Chain	Residue	Details
B	TYR809
C	TYR809

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU01380

Chain	Residue	Details
B	CYS10
B	CYS13
B	CYS27
B	CYS35
C	CYS10
C	CYS13
C	CYS27
C	CYS35

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01125, ECO:0000305\|PubMed:11823434

Chain	Residue	Details
B	GLN61
C	GLN61

site_id	SWS_FT_FI6
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305\|PubMed:11823434

Chain	Residue	Details
B	LYS84
B	THR85
B	SER86
C	LYS84
C	THR85
C	SER86

site_id	SWS_FT_FI7
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01125

Chain	Residue	Details
B	GLU512
C	CYS598
C	CYS601
C	ASP631
B	CYS584
B	CYS587
B	CYS598
B	CYS601
B	ASP631
C	GLU512
C	CYS584
C	CYS587

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1ecl

Chain	Residue	Details
B	GLU512
B	HIS844
B	TYR809
B	ASP631

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1ecl

Chain	Residue	Details
C	GLU512
C	HIS844
C	TYR809
C	ASP631

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)