1GKU
Reverse gyrase from Archaeoglobus fulgidus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003916 | molecular_function | DNA topoisomerase activity |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006265 | biological_process | DNA topological change |
| B | 0006268 | biological_process | DNA unwinding involved in DNA replication |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0160097 | molecular_function | reverse gyrase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | ZN_FING: RG C-terminal-type => ECO:0000255|PROSITE-ProRule:PRU01381 |
| Chain | Residue | Details |
| B | ILE581-SER609 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: O-(5'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01383 |
| Chain | Residue | Details |
| B | TYR809 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01380 |
| Chain | Residue | Details |
| B | CYS35 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01125, ECO:0000305|PubMed:11823434 |
| Chain | Residue | Details |
| B | GLN61 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:11823434 |
| Chain | Residue | Details |
| B | LYS84 | |
| B | THR85 | |
| B | SER86 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01125 |
| Chain | Residue | Details |
| B | GLU512 | |
| B | CYS584 | |
| B | CYS587 | |
| B | CYS598 | |
| B | CYS601 | |
| B | ASP631 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ecl |
| Chain | Residue | Details |
| B | GLU512 | |
| B | HIS844 | |
| B | TYR809 | |
| B | ASP631 |
