1GKP
D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A1460 |
| Chain | Residue |
| A | KCX150 |
| A | HIS183 |
| A | HIS239 |
| A | ZN1461 |
| A | HOH2605 |
| A | HOH2606 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A1461 |
| Chain | Residue |
| A | ASP315 |
| A | ZN1460 |
| A | HOH2606 |
| A | HIS59 |
| A | HIS61 |
| A | KCX150 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A1462 |
| Chain | Residue |
| A | LYS370 |
| A | LYS373 |
| A | HOH2507 |
| A | HOH2508 |
| A | HOH2607 |
| A | HOH2608 |
| A | HOH2609 |
| B | HIS361 |
| B | ARG362 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B1460 |
| Chain | Residue |
| B | KCX150 |
| B | HIS183 |
| B | HIS239 |
| B | ZN1461 |
| B | HOH2584 |
| B | HOH2585 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B1461 |
| Chain | Residue |
| B | HIS59 |
| B | HIS61 |
| B | KCX150 |
| B | ASP315 |
| B | ZN1460 |
| B | HOH2585 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B1462 |
| Chain | Residue |
| A | HIS361 |
| B | LYS370 |
| B | LYS373 |
| B | HOH2472 |
| B | HOH2473 |
| B | HOH2586 |
| B | HOH2587 |
| B | HOH2588 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C1460 |
| Chain | Residue |
| C | KCX150 |
| C | HIS183 |
| C | HIS239 |
| C | ZN1461 |
| C | HOH2654 |
| C | HOH2655 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C1461 |
| Chain | Residue |
| C | HIS59 |
| C | HIS61 |
| C | KCX150 |
| C | ASP315 |
| C | ZN1460 |
| C | HOH2655 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 C1462 |
| Chain | Residue |
| C | LYS370 |
| C | LYS373 |
| C | HOH2548 |
| C | HOH2549 |
| C | HOH2656 |
| C | HOH2657 |
| C | HOH2658 |
| D | HIS361 |
| D | ARG362 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C1463 |
| Chain | Residue |
| C | GLN107 |
| C | LYS110 |
| C | HOH2661 |
| C | HOH2662 |
| F | EPE1463 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D1460 |
| Chain | Residue |
| D | KCX150 |
| D | HIS183 |
| D | HIS239 |
| D | ZN1461 |
| D | HOH2555 |
| D | HOH2556 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D1461 |
| Chain | Residue |
| D | HIS59 |
| D | HIS61 |
| D | KCX150 |
| D | ASP315 |
| D | ZN1460 |
| D | HOH2556 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D1462 |
| Chain | Residue |
| C | HIS361 |
| D | LYS370 |
| D | LYS373 |
| D | HOH2456 |
| D | HOH2457 |
| D | HOH2557 |
| D | HOH2558 |
| D | HOH2559 |
| D | HOH2560 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN E1460 |
| Chain | Residue |
| E | KCX150 |
| E | HIS183 |
| E | HIS239 |
| E | ZN1461 |
| E | HOH2680 |
| E | HOH2681 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN E1461 |
| Chain | Residue |
| E | HOH2681 |
| E | HIS59 |
| E | HIS61 |
| E | KCX150 |
| E | ASP315 |
| E | ZN1460 |
| site_id | BC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 E1462 |
| Chain | Residue |
| E | LYS370 |
| E | LYS373 |
| E | HOH2555 |
| E | HOH2556 |
| E | HOH2682 |
| E | HOH2683 |
| E | HOH2685 |
| E | HOH2687 |
| F | HIS361 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E1463 |
| Chain | Residue |
| D | EPE1463 |
| E | GLN107 |
| E | LYS110 |
| E | HOH2688 |
| E | HOH2689 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E1464 |
| Chain | Residue |
| E | ARG438 |
| E | HOH2690 |
| E | HOH2691 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN F1460 |
| Chain | Residue |
| F | KCX150 |
| F | HIS183 |
| F | HIS239 |
| F | ZN1461 |
| F | HOH2591 |
| F | HOH2592 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN F1461 |
| Chain | Residue |
| F | HIS59 |
| F | HIS61 |
| F | KCX150 |
| F | ASP315 |
| F | ZN1460 |
| F | HOH2592 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 F1462 |
| Chain | Residue |
| E | HIS361 |
| E | HOH2553 |
| F | LYS370 |
| F | LYS373 |
| F | HOH2483 |
| F | HOH2485 |
| F | HOH2594 |
| F | HOH2595 |
| F | HOH2596 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE D1463 |
| Chain | Residue |
| D | VAL428 |
| D | ASP439 |
| D | HOH2524 |
| D | HOH2562 |
| D | HOH2563 |
| D | HOH2564 |
| E | GLN107 |
| E | GLU140 |
| E | SO41463 |
| site_id | CC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE EPE F1463 |
| Chain | Residue |
| C | LEU103 |
| C | GLN107 |
| C | GLU140 |
| C | SO41463 |
| F | SER427 |
| F | VAL428 |
| F | ASP439 |
| F | HOH2597 |
| F | HOH2598 |
| F | HOH2599 |
| F | HOH2600 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| A | ASP315 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| B | ASP315 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| C | ASP315 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| D | ASP315 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| E | ASP315 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| F | ASP315 |
