Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004397 | molecular_function | histidine ammonia-lyase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006547 | biological_process | L-histidine metabolic process |
| B | 0006548 | biological_process | L-histidine catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016841 | molecular_function | ammonia-lyase activity |
| B | 0019556 | biological_process | L-histidine catabolic process to glutamate and formamide |
| B | 0019557 | biological_process | L-histidine catabolic process to glutamate and formate |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 602 |
| Chain | Residue |
| B | TYR53 |
| B | ARG281 |
| B | ASN311 |
| B | SER323 |
| B | PHE327 |
| B | CYS601 |
| B | HOH702 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CYS B 601 |
| Chain | Residue |
| B | ASN193 |
| B | TYR278 |
| B | SO4602 |
| B | HOH702 |
| B | HOH702 |
| B | LEU144 |
| B | LEU189 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE O A 1511 |
| Chain | Residue |
| B | TYR278 |
| B | GLU412 |
| B | CYS601 |
| B | SO4602 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 603 |
| Chain | Residue |
| B | GLY54 |
| B | ILE55 |
| B | ASN56 |
| B | THR57 |
| B | PHE59 |
| B | GLN76 |
| B | LEU79 |
| B | LYS186 |
| B | GLY188 |
| B | LEU189 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. GEGkaRYKGQWLSA |
| Chain | Residue | Details |
| B | GLY158-GLU171 | |
| site_id | PS00488 |
| Number of Residues | 17 |
| Details | PAL_HISTIDASE Phenylalanine and histidine ammonia-lyases signature. GSVGASGDLaPLAhmsL |
| Chain | Residue | Details |
| B | GLY138-LEU154 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"2,3-didehydroalanine (Ser)","evidences":[{"source":"PubMed","id":"7947813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8204579","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"5-imidazolinone (Ala-Gly)"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1b8f |
| Chain | Residue | Details |
| A | ALA142 | |
| A | TYR280 | |
| A | SER143 | |
| A | GLU414 | |
| A | GLY144 | |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 417 |
