Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1GK8

Rubisco from Chlamydomonas reinhardtii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004497	molecular_function	monooxygenase activity
A	0009507	cellular_component	chloroplast
A	0009853	biological_process	photorespiration
A	0015977	biological_process	carbon fixation
A	0015979	biological_process	photosynthesis
A	0016829	molecular_function	lyase activity
A	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
A	0019253	biological_process	reductive pentose-phosphate cycle
A	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004497	molecular_function	monooxygenase activity
C	0009507	cellular_component	chloroplast
C	0009853	biological_process	photorespiration
C	0015977	biological_process	carbon fixation
C	0015979	biological_process	photosynthesis
C	0016829	molecular_function	lyase activity
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
C	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004497	molecular_function	monooxygenase activity
E	0009507	cellular_component	chloroplast
E	0009853	biological_process	photorespiration
E	0015977	biological_process	carbon fixation
E	0015979	biological_process	photosynthesis
E	0016829	molecular_function	lyase activity
E	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
E	0019253	biological_process	reductive pentose-phosphate cycle
E	0046872	molecular_function	metal ion binding
G	0000287	molecular_function	magnesium ion binding
G	0004497	molecular_function	monooxygenase activity
G	0009507	cellular_component	chloroplast
G	0009853	biological_process	photorespiration
G	0015977	biological_process	carbon fixation
G	0015979	biological_process	photosynthesis
G	0016829	molecular_function	lyase activity
G	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
G	0019253	biological_process	reductive pentose-phosphate cycle
G	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1476

Chain	Residue
A	LYS177
A	KCX201
A	ASP203
A	GLU204
A	CAP1477

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1476

Chain	Residue
C	CAP1477
C	LYS177
C	KCX201
C	ASP203
C	GLU204

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E 1476

Chain	Residue
E	LYS177
E	KCX201
E	ASP203
E	GLU204
E	CAP1477

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG G 1476

Chain	Residue
G	KCX201
G	ASP203
G	GLU204
G	CAP1477

site_id	AC5
Number of Residues	28
Details	BINDING SITE FOR RESIDUE CAP A 1477

Chain	Residue
A	GLU60
A	THR65
A	TRP66
A	ASN123
A	THR173
A	LYS175
A	LYS177
A	KCX201
A	ASP203
A	GLU204
A	HIS294
A	ARG295
A	HIS327
A	LYS334
A	LEU335
A	SER379
A	GLY380
A	GLY381
A	GLY403
A	GLY404
A	MG1476
A	HOH2153
A	HOH2443
A	HOH2444
A	HOH2445
A	HOH2446
A	HOH2447
A	HOH2448

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO A 1478

Chain	Residue
A	TYR24
A	GLY64
A	THR68
A	VAL69
A	ASP72
A	LEU77
A	HOH2449
A	HOH2450
A	HOH2451

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1479

Chain	Residue
A	VAL17
A	LYS18
A	THR65
A	TRP66
A	THR67
A	THR68
A	HOH2451
A	HOH2452

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1480

Chain	Residue
A	GLU52
A	HOH2453
A	HOH2454
A	HOH2455

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1481

Chain	Residue
A	GLY47
A	VAL48
A	PRO49
A	GLU52
A	HOH2022
A	HOH2455
A	HOH2456
A	HOH2457

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1482

Chain	Residue
A	LYS466
A	PHE467
A	GLU468
A	PHE469
A	HOH2453
A	HOH2458

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1483

Chain	Residue
A	HIS298
A	PHE311
A	GLU336
A	ASP473
A	HOH2286
A	HOH2310
A	HOH2459
A	HOH2460

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1484

Chain	Residue
A	LEU270
A	LEU270
A	HOH2461
A	HOH2461

site_id	BC4
Number of Residues	28
Details	BINDING SITE FOR RESIDUE CAP C 1477

Chain	Residue
C	GLU204
C	HIS294
C	ARG295
C	HIS327
C	LYS334
C	LEU335
C	SER379
C	GLY380
C	GLY381
C	GLY403
C	GLY404
C	MG1476
C	HOH2453
C	HOH2454
C	HOH2455
C	HOH2456
C	HOH2457
C	HOH2458
G	GLU60
G	THR65
G	TRP66
G	ASN123
G	HOH2174
C	THR173
C	LYS175
C	LYS177
C	KCX201
C	ASP203

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO C 1478

Chain	Residue
C	TYR24
C	GLY64
C	THR68
C	VAL69
C	ASP72
C	LEU77
C	EDO1479
C	HOH2459
C	HOH2460
C	HOH2461

site_id	BC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO C 1479

Chain	Residue
C	GLY16
C	VAL17
C	LYS18
C	THR65
C	TRP66
C	THR67
C	THR68
C	EDO1478
C	HOH2043
C	HOH2461

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO C 1480

Chain	Residue
C	GLU52
C	HOH2462
C	HOH2463

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 1481

Chain	Residue
C	LYS466
C	PHE467
C	GLU468
C	PHE469
C	HOH2464
G	HOH2470

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO C 1482

Chain	Residue
C	HIS298
C	PHE311
C	GLU336
C	ASP473
C	HOH2286
C	HOH2309
C	HOH2465
C	HOH2466

site_id	CC1
Number of Residues	28
Details	BINDING SITE FOR RESIDUE CAP E 1477

Chain	Residue
E	GLU60
E	THR65
E	TRP66
E	ASN123
E	THR173
E	LYS175
E	LYS177
E	KCX201
E	ASP203
E	GLU204
E	HIS294
E	ARG295
E	HIS327
E	LYS334
E	LEU335
E	SER379
E	GLY380
E	GLY381
E	GLY403
E	GLY404
E	MG1476
E	HOH2161
E	HOH2469
E	HOH2470
E	HOH2471
E	HOH2472
E	HOH2473
E	HOH2474

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO E 1478

Chain	Residue
E	TYR24
E	GLY64
E	THR68
E	VAL69
E	ASP72
E	LEU77
E	HOH2475
E	HOH2476
E	HOH2478

site_id	CC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 1479

Chain	Residue
E	VAL17
E	LYS18
E	THR65
E	TRP66
E	THR67
E	THR68
E	HOH2477
E	HOH2478

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO E 1480

Chain	Residue
E	GLU52
E	EDO1481
E	HOH2479
E	HOH2480
E	HOH2483

site_id	CC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO E 1481

Chain	Residue
E	GLY47
E	VAL48
E	PRO49
E	GLU52
E	EDO1480
E	HOH2018
E	HOH2481
E	HOH2482
E	HOH2483

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 1482

Chain	Residue
E	LYS466
E	PHE467
E	GLU468
E	PHE469
E	HOH2480
E	HOH2484

site_id	CC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 1483

Chain	Residue
E	HIS298
E	PHE311
E	GLU336
E	ASP473
E	HOH2301
E	HOH2325
E	HOH2485
E	HOH2486

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO E 1484

Chain	Residue
E	LEU270
E	LEU270
E	HOH2487
E	HOH2487

site_id	CC9
Number of Residues	28
Details	BINDING SITE FOR RESIDUE CAP G 1477

Chain	Residue
C	GLU60
C	THR65
C	TRP66
C	ASN123
C	HOH2150
G	THR173
G	LYS175
G	LYS177
G	KCX201
G	ASP203
G	GLU204
G	HIS294
G	ARG295
G	HIS327
G	LYS334
G	LEU335
G	SER379
G	GLY380
G	GLY381
G	GLY403
G	GLY404
G	MG1476
G	HOH2458
G	HOH2459
G	HOH2460
G	HOH2461
G	HOH2462
G	HOH2463

site_id	DC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO G 1478

Chain	Residue
G	TYR24
G	GLY64
G	THR68
G	VAL69
G	ASP72
G	LEU77
G	HOH2464
G	HOH2465
G	HOH2466

site_id	DC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO G 1479

Chain	Residue
G	VAL17
G	LYS18
G	THR65
G	TRP66
G	THR67
G	THR68
G	HOH2466
G	HOH2467

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO G 1480

Chain	Residue
G	GLU52
G	HOH2468
G	HOH2470

site_id	DC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO G 1481

Chain	Residue
C	HOH2463
G	GLU464
G	LYS466
G	PHE467
G	GLU468
G	PHE469
G	HOH2442

site_id	DC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO G 1482

Chain	Residue
G	HIS298
G	PHE311
G	GLU336
G	ASP473
G	HOH2300
G	HOH2326
G	HOH2471
G	HOH2472

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO G 1483

Chain	Residue
C	LEU270
G	LEU270
G	HOH2473
G	HOH2474

site_id	DC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO I 1127

Chain	Residue
C	TYR226
C	HOH2237
I	LYS49
I	GLU55
I	HOH2104

site_id	DC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO I 1128

Chain	Residue
I	GLY37
I	TRP38
I	ILE39
I	PHE81
I	GLY82
I	CYS83
I	HOH2157

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO K 1127

Chain	Residue
E	TYR226
E	HOH2251
K	LYS49
K	GLU55
K	HOH2110
K	HOH2166

site_id	EC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO K 1128

Chain	Residue
K	GLY37
K	TRP38
K	ILE39
K	GLY82
K	CYS83
K	HOH2167
K	HOH2168

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO M 1127

Chain	Residue
G	TYR226
G	HOH2254
M	LYS49
M	GLU55
M	HOH2113
M	HOH2168

site_id	EC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO M 1128

Chain	Residue
M	GLY37
M	TRP38
M	ILE39
M	GLY82
M	CYS83
M	ARG84
M	HOH2170

site_id	EC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO O 1127

Chain	Residue
A	TYR226
A	ALA230
A	HOH2237
O	LYS49
O	GLU55
O	HOH2113
O	HOH2171

site_id	EC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO O 1128

Chain	Residue
O	GLY37
O	TRP38
O	ILE39
O	GLY82
O	CYS83
O	HOH2172

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
A	GLY196-GLU204

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N-methylmethionine => ECO:0000269\|PubMed:11641402

Chain	Residue	Details
I	MME1
K	MME1
M	MME1
O	MME1
E	LYS175
E	HIS294
G	LYS175
G	HIS294

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: in homodimeric partner

Chain	Residue	Details
A	ASN123
C	ASN123
E	ASN123
G	ASN123

site_id	SWS_FT_FI3
Number of Residues	20
Details	BINDING:

Chain	Residue	Details
A	THR173
C	SER379
E	THR173
E	LYS177
E	ARG295
E	HIS327
E	SER379
G	THR173
G	LYS177
G	ARG295
G	HIS327
A	LYS177
G	SER379
A	ARG295
A	HIS327
A	SER379
C	THR173
C	LYS177
C	ARG295
C	HIS327

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: via carbamate group => ECO:0000269\|PubMed:11641402, ECO:0000269\|PubMed:11866526

Chain	Residue	Details
A	KCX201
C	KCX201
E	KCX201
G	KCX201

site_id	SWS_FT_FI5
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269\|PubMed:11641402, ECO:0000269\|PubMed:11866526

Chain	Residue	Details
A	ASP203
A	GLU204
C	ASP203
C	GLU204
E	ASP203
E	GLU204
G	ASP203
G	GLU204

site_id	SWS_FT_FI6
Number of Residues	4
Details	SITE: Transition state stabilizer

Chain	Residue	Details
A	LYS334
C	LYS334
E	LYS334
G	LYS334

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N-acetylproline => ECO:0000269\|PubMed:16668742

Chain	Residue	Details
A	PRO3
C	PRO3
E	PRO3
G	PRO3

site_id	SWS_FT_FI8
Number of Residues	8
Details	MOD_RES: 4-hydroxyproline => ECO:0000269\|PubMed:11641402, ECO:0000269\|PubMed:11866526

Chain	Residue	Details
A	HYP104
A	HYP151
C	HYP104
C	HYP151
E	HYP104
E	HYP151
G	HYP104
G	HYP151

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: N6-carboxylysine => ECO:0000269\|PubMed:11641402, ECO:0000269\|PubMed:11866526, ECO:0000269\|PubMed:6302265

Chain	Residue	Details
A	KCX201
C	KCX201
E	KCX201
G	KCX201

site_id	SWS_FT_FI10
Number of Residues	8
Details	MOD_RES: S-methylcysteine => ECO:0000269\|PubMed:11641402, ECO:0000269\|PubMed:11866526

Chain	Residue	Details
A	SMC256
A	SMC369
C	SMC256
C	SMC369
E	SMC256
E	SMC369
G	SMC256
G	SMC369

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
A	LYS175
A	HIS294
A	LYS177
A	ASP203
A	HIS327

site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
C	LYS175
C	HIS294
C	LYS177
C	ASP203
C	HIS327

site_id	CSA3
Number of Residues	5
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
E	LYS175
E	HIS294
E	LYS177
E	ASP203
E	HIS327

site_id	CSA4
Number of Residues	5
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
G	LYS175
G	HIS294
G	LYS177
G	ASP203
G	HIS327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)