1GK3
Histidine Ammonia-Lyase (HAL) Mutant D145A from Pseudomonas putida
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1510 |
| Chain | Residue |
| A | TYR53 |
| A | LEU191 |
| A | ASN195 |
| A | ASN313 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 1511 |
| Chain | Residue |
| A | LEU79 |
| A | ALA187 |
| A | LYS188 |
| A | LEU191 |
| A | HOH2039 |
| A | GLY54 |
| A | ILE55 |
| A | ASN56 |
| A | THR57 |
| A | PHE59 |
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. GEGkaRYKGQWLSA |
| Chain | Residue | Details |
| A | GLY158-ALA171 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"2,3-didehydroalanine (Ser)","evidences":[{"source":"PubMed","id":"10220322","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7947813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8204579","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"5-imidazolinone (Ala-Gly)","evidences":[{"source":"PubMed","id":"10220322","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1b8f |
| Chain | Residue | Details |
| A | ALA142 | |
| A | TYR280 | |
| A | SER143 | |
| A | GLU414 | |
| A | GLY144 |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 417 |
| Chain | Residue | Details |
| A | TYR53 | electrostatic stabiliser |
| A | HIS83 | electrostatic stabiliser |
| A | ASN195 | activator |
| A | TYR280 | proton shuttle (general acid/base) |
| A | ARG283 | electrostatic stabiliser |
| A | PHE329 | electrostatic stabiliser |
| A | GLU414 | proton shuttle (general acid/base) |
