1GG1
CRYSTAL STRUCTURE ANALYSIS OF DAHP SYNTHASE IN COMPLEX WITH MN2+ AND 2-PHOSPHOGLYCOLATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PGA A 372 |
| Chain | Residue |
| A | ARG92 |
| A | GLU302 |
| A | MN371 |
| A | HOH1389 |
| A | HOH1415 |
| A | HOH1424 |
| A | HOH1453 |
| A | TYR94 |
| A | LYS97 |
| A | GLY163 |
| A | ALA164 |
| A | ARG165 |
| A | LYS186 |
| A | ARG234 |
| A | HIS268 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PGA B 372 |
| Chain | Residue |
| B | ARG92 |
| B | LYS97 |
| B | GLY163 |
| B | ALA164 |
| B | ARG165 |
| B | LYS186 |
| B | ARG234 |
| B | HIS268 |
| B | GLU302 |
| B | MN371 |
| B | HOH2375 |
| B | HOH2385 |
| B | HOH2438 |
| B | HOH2472 |
| B | HOH2546 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PGA C 372 |
| Chain | Residue |
| C | ARG92 |
| C | TYR94 |
| C | LYS97 |
| C | GLY163 |
| C | ALA164 |
| C | ARG165 |
| C | LYS186 |
| C | ARG234 |
| C | HIS268 |
| C | GLU302 |
| C | MN371 |
| C | HOH3375 |
| C | HOH3417 |
| C | HOH3433 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PGA D 372 |
| Chain | Residue |
| D | ARG92 |
| D | TYR94 |
| D | LYS97 |
| D | GLY163 |
| D | ALA164 |
| D | ARG165 |
| D | LYS186 |
| D | ARG234 |
| D | HIS268 |
| D | GLU302 |
| D | MN371 |
| D | HOH4375 |
| D | HOH4424 |
| D | HOH4434 |
| D | HOH4445 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 371 |
| Chain | Residue |
| A | CYS61 |
| A | LYS97 |
| A | HIS268 |
| A | GLU302 |
| A | ASP326 |
| A | PGA372 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 371 |
| Chain | Residue |
| B | CYS61 |
| B | HIS268 |
| B | GLU302 |
| B | ASP326 |
| B | PGA372 |
| B | HOH2375 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN C 371 |
| Chain | Residue |
| C | CYS61 |
| C | HIS268 |
| C | GLU302 |
| C | ASP326 |
| C | PGA372 |
| C | HOH3375 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN D 371 |
| Chain | Residue |
| D | CYS61 |
| D | HIS268 |
| D | GLU302 |
| D | ASP326 |
| D | PGA372 |
| D | HOH4375 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1373 |
| Chain | Residue |
| A | ARG99 |
| A | THR100 |
| A | HOH1451 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2373 |
| Chain | Residue |
| B | ARG99 |
| B | THR100 |
| B | HOH2411 |
| B | HOH2596 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3373 |
| Chain | Residue |
| C | ARG99 |
| C | THR100 |
| C | HOH3418 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 4373 |
| Chain | Residue |
| D | ARG99 |
| D | THR100 |
| D | HOH4433 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1374 |
| Chain | Residue |
| A | THR192 |
| A | ILE193 |
| A | LYS194 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2374 |
| Chain | Residue |
| B | THR192 |
| B | ILE193 |
| B | LYS194 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 3374 |
| Chain | Residue |
| C | THR192 |
| C | ILE193 |
| C | LYS194 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 4374 |
| Chain | Residue |
| D | THR192 |
| D | ILE193 |
| D | LYS194 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842 |
| Chain | Residue | Details |
| A | LYS244 | |
| B | LYS244 | |
| C | LYS244 | |
| D | LYS244 |
