1GC6

CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0008092	molecular_function	cytoskeletal protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE I3P A 1229

Chain	Residue
A	LYS60
A	ASN62
A	LYS63
A	LYS278

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Functional Information from PROSITE/UniProt

site_id	PS00660
Number of Residues	31
Details	FERM_1 FERM domain signature 1. WLklnKkVtqQd.Vkkenplq.FkfrakFFpeD

Chain	Residue	Details
A	TRP58-ASP88

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site_id	PS00661
Number of Residues	30
Details	FERM_2 FERM domain signature 2. HeehrgmlreDSmmeYLki.AqdLemYGvNY

Chain	Residue	Details
A	HIS176-TYR205

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	290
Details	Domain: {"description":"FERM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00084","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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