Functional Information from GO Data
Chain | GOid | namespace | contents |
E | 0004175 | molecular_function | endopeptidase activity |
E | 0004252 | molecular_function | serine-type endopeptidase activity |
E | 0005515 | molecular_function | protein binding |
E | 0005576 | cellular_component | extracellular region |
E | 0005615 | cellular_component | extracellular space |
E | 0006508 | biological_process | proteolysis |
E | 0007586 | biological_process | digestion |
E | 0008236 | molecular_function | serine-type peptidase activity |
E | 0046872 | molecular_function | metal ion binding |
E | 0097180 | cellular_component | serine protease inhibitor complex |
E | 0097655 | molecular_function | serpin family protein binding |
I | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
I | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA E 801 |
Chain | Residue |
E | GLU70 |
E | ASN72 |
E | VAL75 |
E | GLU80 |
E | HOH470 |
E | HOH519 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 E 802 |
Chain | Residue |
E | GLN240 |
E | HOH432 |
E | HOH454 |
E | HOH584 |
E | HOH701 |
E | LYS169 |
E | PRO173 |
E | GLY174 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 E 803 |
Chain | Residue |
E | ARG66 |
E | PHE82 |
E | SER166 |
E | SER167 |
E | SER170 |
E | HOH482 |
E | HOH673 |
E | HOH680 |
site_id | AC4 |
Number of Residues | 27 |
Details | BINDING SITE FOR CHAIN I OF BOWMAN-BIRK TYPE TRYPSIN INHIBITOR |
Chain | Residue |
E | HIS40 |
E | PHE41 |
E | HIS57 |
E | SER96 |
E | ASN97 |
E | THR98 |
E | LEU99 |
E | GLY133 |
E | TYR151 |
E | GLN175 |
E | ASP189 |
E | SER190 |
E | CYS191 |
E | GLN192 |
E | GLY193 |
E | ASP194 |
E | SER195 |
E | SER214 |
E | TRP215 |
E | GLY216 |
E | SER217 |
E | HOH528 |
I | HOH525 |
I | HOH572 |
I | HOH587 |
I | HOH657 |
I | HOH676 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
E | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
Chain | Residue | Details |
E | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | SITE: Reactive bond for trypsin |
Chain | Residue | Details |
I | LYS311 | |
E | LEU105 | |
E | PRO198 | |
site_id | SWS_FT_FI2 |
Number of Residues | 7 |
Details | BINDING: |
Chain | Residue | Details |
E | ILE73 | |
E | VAL75 | |
E | GLY78 | |
E | ILE83 | |
E | GLN192 | |
E | SER195 | |
E | PRO198 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER195 | |
E | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER195 | |
E | GLY193 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | HIS57 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | GLY193 | |
E | HIS57 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP102 | |
E | SER195 | |
E | HIS57 | |
E | GLY196 | |