Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008289 | molecular_function | lipid binding |
A | 0008320 | molecular_function | protein transmembrane transporter activity |
A | 0016020 | cellular_component | membrane |
A | 0020002 | cellular_component | host cell plasma membrane |
A | 0030430 | cellular_component | host cell cytoplasm |
A | 0035821 | biological_process | modulation of process of another organism |
A | 0044161 | cellular_component | host cell cytoplasmic vesicle |
A | 0044164 | cellular_component | host cell cytosol |
A | 0044221 | cellular_component | host cell synapse |
A | 0044231 | cellular_component | host cell presynaptic membrane |
A | 0046872 | molecular_function | metal ion binding |
A | 0071806 | biological_process | protein transmembrane transport |
A | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 1291 |
Chain | Residue |
A | HIS229 |
A | HIS233 |
A | HOH1308 |
A | HOH1341 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE ZN A 1294 |
Chain | Residue |
A | GLN258 |
A | BAB1292 |
site_id | AC3 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE BAB A 1292 |
Chain | Residue |
A | TYR372 |
A | PHE373 |
A | SER374 |
A | ASP375 |
A | SER376 |
A | GLU451 |
A | LEU453 |
A | PHE454 |
A | PHE455 |
A | THR709 |
A | GLN710 |
A | TYR712 |
A | THR713 |
A | ZN1294 |
A | HOH1408 |
A | HOH1658 |
A | ASP68 |
A | GLN258 |
A | ARG369 |
site_id | AC4 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE BAB A 1293 |
Chain | Residue |
A | ASN203 |
A | ARG217 |
A | ASP375 |
A | LEU377 |
A | ASP447 |
A | ASP452 |
A | PHE537 |
A | LEU540 |
A | GLU716 |
A | LYS720 |
A | TYR724 |
A | HOH1484 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. ILMHELIHVL |
Chain | Residue | Details |
A | ILE226-LEU235 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LEU231 | |
Chain | Residue | Details |
A | GLU230 | |
A | VAL234 | |
Chain | Residue | Details |
A | LEU268 | |
Chain | Residue | Details |
A | THR1025 | |
Chain | Residue | Details |
A | GLU1189 | |
A | HIS1240 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1i1e |
Chain | Residue | Details |
A | TYR372 | |
A | ARG369 | |
A | GLU267 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 626 |
Chain | Residue | Details |
A | GLU230 | metal ligand |
A | LEU231 | proton acceptor, proton donor |
A | VAL234 | metal ligand |
A | LEU268 | metal ligand |
A | ALA370 | electrostatic stabiliser |