Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1G5I

CRYSTAL STRUCTURE OF THE ACCESSORY SUBUNIT OF MURINE MITOCHONDRIAL POLYMERASE GAMMA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001701	biological_process	in utero embryonic development
A	0003677	molecular_function	DNA binding
A	0003690	molecular_function	double-stranded DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005760	cellular_component	gamma DNA polymerase complex
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006264	biological_process	mitochondrial DNA replication
A	0006281	biological_process	DNA repair
A	0007005	biological_process	mitochondrion organization
A	0030337	molecular_function	DNA polymerase processivity factor activity
A	0032042	biological_process	mitochondrial DNA metabolic process
A	0042645	cellular_component	mitochondrial nucleoid
A	0042802	molecular_function	identical protein binding
A	0070182	molecular_function	DNA polymerase binding
A	0071897	biological_process	DNA biosynthetic process
B	0001701	biological_process	in utero embryonic development
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003887	molecular_function	DNA-directed DNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005760	cellular_component	gamma DNA polymerase complex
B	0006260	biological_process	DNA replication
B	0006261	biological_process	DNA-templated DNA replication
B	0006264	biological_process	mitochondrial DNA replication
B	0006281	biological_process	DNA repair
B	0007005	biological_process	mitochondrion organization
B	0030337	molecular_function	DNA polymerase processivity factor activity
B	0032042	biological_process	mitochondrial DNA metabolic process
B	0042645	cellular_component	mitochondrial nucleoid
B	0042802	molecular_function	identical protein binding
B	0070182	molecular_function	DNA polymerase binding
B	0071897	biological_process	DNA biosynthetic process
C	0001701	biological_process	in utero embryonic development
C	0003677	molecular_function	DNA binding
C	0003690	molecular_function	double-stranded DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0005760	cellular_component	gamma DNA polymerase complex
C	0006260	biological_process	DNA replication
C	0006261	biological_process	DNA-templated DNA replication
C	0006264	biological_process	mitochondrial DNA replication
C	0006281	biological_process	DNA repair
C	0007005	biological_process	mitochondrion organization
C	0030337	molecular_function	DNA polymerase processivity factor activity
C	0032042	biological_process	mitochondrial DNA metabolic process
C	0042645	cellular_component	mitochondrial nucleoid
C	0042802	molecular_function	identical protein binding
C	0070182	molecular_function	DNA polymerase binding
C	0071897	biological_process	DNA biosynthetic process
D	0001701	biological_process	in utero embryonic development
D	0003677	molecular_function	DNA binding
D	0003690	molecular_function	double-stranded DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0005760	cellular_component	gamma DNA polymerase complex
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006264	biological_process	mitochondrial DNA replication
D	0006281	biological_process	DNA repair
D	0007005	biological_process	mitochondrion organization
D	0030337	molecular_function	DNA polymerase processivity factor activity
D	0032042	biological_process	mitochondrial DNA metabolic process
D	0042645	cellular_component	mitochondrial nucleoid
D	0042802	molecular_function	identical protein binding
D	0070182	molecular_function	DNA polymerase binding
D	0071897	biological_process	DNA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 901

Chain	Residue
A	VAL93
A	ARG96
A	VAL99
A	HOH911
A	HOH920
A	HOH978

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 902

Chain	Residue
C	HOH982
D	HOH968
C	VAL93
C	ARG96
C	VAL99

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 903

Chain	Residue
A	HOH1009
B	VAL93
B	ARG96
B	VAL99
B	HOH942
B	HOH992

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA D 904

Chain	Residue
D	VAL93
D	ARG96
D	VAL99

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL D 5

Chain	Residue
C	ASP103
C	HIS106
D	ARG81
D	GLU207
D	LYS208
D	THR209
D	ASP317
D	HOH919
D	HOH1018

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL B 6

Chain	Residue
A	ASP103
A	HIS106
B	ARG81
B	GLU207
B	LYS208
B	THR209
B	ASP317
B	HOH910
B	HOH982

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
A	HIS190

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
B	HIS190

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
C	HIS190

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1qf6

Chain	Residue	Details
D	HIS190

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)