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1G2T

SOLUTION STRUCTURE OF EOTAXIN-3

Functional Information from GO Data
ChainGOidnamespacecontents
A0001938biological_processpositive regulation of endothelial cell proliferation
A0002548biological_processmonocyte chemotaxis
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006935biological_processchemotaxis
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007165biological_processsignal transduction
A0007186biological_processG protein-coupled receptor signaling pathway
A0007267biological_processcell-cell signaling
A0008009molecular_functionchemokine activity
A0010818biological_processT cell chemotaxis
A0030335biological_processpositive regulation of cell migration
A0030593biological_processneutrophil chemotaxis
A0030838biological_processpositive regulation of actin filament polymerization
A0031728molecular_functionCCR3 chemokine receptor binding
A0031737molecular_functionCX3C chemokine receptor binding
A0043547biological_processpositive regulation of GTPase activity
A0048018molecular_functionreceptor ligand activity
A0048020molecular_functionCCR chemokine receptor binding
A0048245biological_processeosinophil chemotaxis
A0048247biological_processlymphocyte chemotaxis
A0050921biological_processpositive regulation of chemotaxis
A0070098biological_processchemokine-mediated signaling pathway
A0070374biological_processpositive regulation of ERK1 and ERK2 cascade
A0071346biological_processcellular response to type II interferon
A0071347biological_processcellular response to interleukin-1
A0071356biological_processcellular response to tumor necrosis factor
Functional Information from PROSITE/UniProt
site_idPS00472
Number of Residues42
DetailsSMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCFqyshkp..LpwtwVrsYeftsns..Csqr.AVIFttkrgkkv.CT
ChainResidueDetails
ACYS10-THR51

217705

PDB entries from 2024-03-27

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