1G2G

MINIMAL CONFORMATION OF THE ALPHA-CONOTOXIN IMI FOR THE ALPHA7 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR RECOGNITION

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NH2 A 13

Chain	Residue
A	ALA9
A	CYS12

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Functional Information from PROSITE/UniProt

site_id	PS60014
Number of Residues	11
Details	ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCSdPRCA....WRC

Chain	Residue	Details
A	CYS2-CYS12

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Peptide: {"description":"Alpha-conotoxin ImI","featureId":"PRO_0000034877","evidences":[{"source":"PubMed","id":"8206995","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Site: {"description":"Important for binding to human alpha-7 nAChR","evidences":[{"source":"PubMed","id":"15609996","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Cysteine amide","evidences":[{"source":"PubMed","id":"8206995","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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