1G25

SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN TFIIH MAT1 SUBUNIT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005675	cellular_component	transcription factor TFIIH holo complex
A	0006289	biological_process	nucleotide-excision repair
A	0045737	biological_process	positive regulation of cyclin-dependent protein serine/threonine kinase activity
A	0061575	molecular_function	cyclin-dependent protein serine/threonine kinase activator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 66

Chain	Residue
A	CYS6
A	CYS9
A	CYS31
A	SER33
A	CYS34

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 67

Chain	Residue
A	CYS26
A	HIS28
A	CYS46
A	CYS49

---

Functional Information from PROSITE/UniProt

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CgHtLCesCV

Chain	Residue	Details
A	CYS26-VAL35

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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