1G0I
CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE-FRUCTOSE 1,6 BISPHOSPHATASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006020 | biological_process | inositol metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| A | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| A | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| A | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
| B | 0006020 | biological_process | inositol metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0008934 | molecular_function | inositol monophosphate 1-phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042132 | molecular_function | fructose 1,6-bisphosphate 1-phosphatase activity |
| B | 0046854 | biological_process | phosphatidylinositol phosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052832 | molecular_function | inositol monophosphate 3-phosphatase activity |
| B | 0052833 | molecular_function | inositol monophosphate 4-phosphatase activity |
| B | 0052834 | molecular_function | inositol monophosphate phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 290 |
| Chain | Residue |
| A | ASP81 |
| A | ASP84 |
| A | ASP201 |
| A | MN291 |
| A | PO4293 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 291 |
| Chain | Residue |
| A | PO4293 |
| A | HOH635 |
| A | GLU65 |
| A | ASP81 |
| A | ILE83 |
| A | MN290 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 292 |
| Chain | Residue |
| A | ASP38 |
| A | GLU65 |
| A | PO4293 |
| A | HOH634 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PO4 A 293 |
| Chain | Residue |
| A | GLU65 |
| A | ASP81 |
| A | ILE83 |
| A | ASP84 |
| A | GLY85 |
| A | SER86 |
| A | ARG198 |
| A | ASP201 |
| A | MN290 |
| A | MN291 |
| A | MN292 |
| A | HOH634 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 590 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ILE383 |
| B | PO4593 |
| B | HOH644 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 591 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ASP384 |
| B | ASP501 |
| B | PO4593 |
| B | HOH629 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 592 |
| Chain | Residue |
| B | ASP338 |
| B | GLU365 |
| B | ARG498 |
| B | PO4593 |
| B | HOH645 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 B 593 |
| Chain | Residue |
| B | GLU365 |
| B | ASP381 |
| B | ILE383 |
| B | ASP384 |
| B | GLY385 |
| B | SER386 |
| B | ARG498 |
| B | MN590 |
| B | MN591 |
| B | MN592 |
| B | HOH645 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE INS B 294 |
| Chain | Residue |
| A | GLY173 |
| B | LYS467 |
| B | ARG468 |
| B | VAL469 |
| B | ARG470 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE INS A 594 |
| Chain | Residue |
| A | ARG168 |
| A | ARG170 |
| B | TYR452 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:11062561, ECO:0000305|PubMed:11170378 |
| Chain | Residue | Details |
| A | GLU65 | |
| B | ASP501 | |
| A | ASP81 | |
| A | ILE83 | |
| A | ASP84 | |
| A | ASP201 | |
| B | GLU365 | |
| B | ASP381 | |
| B | ILE383 | |
| B | ASP384 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11170378 |
| Chain | Residue | Details |
| A | ARG170 | |
| A | PHE175 | |
| A | ARG194 | |
| B | ARG470 | |
| B | PHE475 | |
| B | ARG494 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| A | ASP38 | |
| A | ASP44 | |
| A | GLU66 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| B | ASP338 | |
| B | GLU366 | |
| B | ASP344 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| A | SER86 | |
| A | GLU65 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eyi |
| Chain | Residue | Details |
| B | SER386 | |
| B | GLU365 |
