1FZ9
Methane monooxygenase hydroxylase, form II cocrystallized with iodoethane
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0006730 | biological_process | one-carbon metabolic process |
| E | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| E | 0015947 | biological_process | methane metabolic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| F | 0004497 | molecular_function | monooxygenase activity |
| F | 0006730 | biological_process | one-carbon metabolic process |
| F | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| F | 0015947 | biological_process | methane metabolic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE A 5001 |
| Chain | Residue |
| A | GLU114 |
| A | GLU144 |
| A | HIS147 |
| A | GLU243 |
| A | FE5002 |
| A | HOH9192 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 5002 |
| Chain | Residue |
| A | HIS246 |
| A | FE5001 |
| A | GLU144 |
| A | GLU209 |
| A | GLU243 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE B 5003 |
| Chain | Residue |
| B | GLU114 |
| B | GLU144 |
| B | HIS147 |
| B | FE5004 |
| B | HOH9150 |
| B | HOH9151 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE B 5004 |
| Chain | Residue |
| B | GLU144 |
| B | GLU209 |
| B | GLU243 |
| B | HIS246 |
| B | FE5003 |
| B | HOH9151 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 5005 |
| Chain | Residue |
| A | ASN527 |
| B | SER428 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA C 5006 |
| Chain | Residue |
| C | ASP348 |
| C | HOH9008 |
| C | HOH9130 |
| C | HOH9146 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA C 5007 |
| Chain | Residue |
| C | GLU222 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ETI D 9001 |
| Chain | Residue |
| C | TYR119 |
| D | GLU116 |
| D | GLN283 |
| D | TYR287 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ETI D 9002 |
| Chain | Residue |
| C | GLU116 |
| C | THR286 |
| D | TYR119 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ETI A 9003 |
| Chain | Residue |
| A | THR102 |
| A | GLY293 |
| A | LEU361 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ETI A 9004 |
| Chain | Residue |
| A | VAL106 |
| A | LEU216 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ETI B 9005 |
| Chain | Residue |
| B | VAL106 |
| B | LEU216 |
| B | LEU289 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ETI B 9006 |
| Chain | Residue |
| B | LEU289 |
| B | LEU361 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ETI C 9007 |
| Chain | Residue |
| C | GLN125 |
| D | ILE290 |
| D | GLN293 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ETI D 9008 |
| Chain | Residue |
| C | GLN293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| A | CYS151 | |
| A | THR213 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| B | CYS151 | |
| B | THR213 |
