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1FUJ

PR3 (MYELOBLASTIN)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0005102molecular_functionsignaling receptor binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006508biological_processproteolysis
A0006509biological_processmembrane protein ectodomain proteolysis
A0008236molecular_functionserine-type peptidase activity
A0008284biological_processpositive regulation of cell population proliferation
A0019730biological_processantimicrobial humoral response
A0019899molecular_functionenzyme binding
A0030574biological_processcollagen catabolic process
A0035578cellular_componentazurophil granule lumen
A0043231cellular_componentintracellular membrane-bounded organelle
A0043547biological_processpositive regulation of GTPase activity
A0044853cellular_componentplasma membrane raft
A0045121cellular_componentmembrane raft
A0045217biological_processcell-cell junction maintenance
A0050765biological_processnegative regulation of phagocytosis
A0062023cellular_componentcollagen-containing extracellular matrix
A0070062cellular_componentextracellular exosome
A0072672biological_processneutrophil extravasation
A0097029biological_processmature conventional dendritic cell differentiation
B0004252molecular_functionserine-type endopeptidase activity
B0005102molecular_functionsignaling receptor binding
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006508biological_processproteolysis
B0006509biological_processmembrane protein ectodomain proteolysis
B0008236molecular_functionserine-type peptidase activity
B0008284biological_processpositive regulation of cell population proliferation
B0019730biological_processantimicrobial humoral response
B0019899molecular_functionenzyme binding
B0030574biological_processcollagen catabolic process
B0035578cellular_componentazurophil granule lumen
B0043231cellular_componentintracellular membrane-bounded organelle
B0043547biological_processpositive regulation of GTPase activity
B0044853cellular_componentplasma membrane raft
B0045121cellular_componentmembrane raft
B0045217biological_processcell-cell junction maintenance
B0050765biological_processnegative regulation of phagocytosis
B0062023cellular_componentcollagen-containing extracellular matrix
B0070062cellular_componentextracellular exosome
B0072672biological_processneutrophil extravasation
B0097029biological_processmature conventional dendritic cell differentiation
C0004252molecular_functionserine-type endopeptidase activity
C0005102molecular_functionsignaling receptor binding
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006508biological_processproteolysis
C0006509biological_processmembrane protein ectodomain proteolysis
C0008236molecular_functionserine-type peptidase activity
C0008284biological_processpositive regulation of cell population proliferation
C0019730biological_processantimicrobial humoral response
C0019899molecular_functionenzyme binding
C0030574biological_processcollagen catabolic process
C0035578cellular_componentazurophil granule lumen
C0043231cellular_componentintracellular membrane-bounded organelle
C0043547biological_processpositive regulation of GTPase activity
C0044853cellular_componentplasma membrane raft
C0045121cellular_componentmembrane raft
C0045217biological_processcell-cell junction maintenance
C0050765biological_processnegative regulation of phagocytosis
C0062023cellular_componentcollagen-containing extracellular matrix
C0070062cellular_componentextracellular exosome
C0072672biological_processneutrophil extravasation
C0097029biological_processmature conventional dendritic cell differentiation
D0004252molecular_functionserine-type endopeptidase activity
D0005102molecular_functionsignaling receptor binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006508biological_processproteolysis
D0006509biological_processmembrane protein ectodomain proteolysis
D0008236molecular_functionserine-type peptidase activity
D0008284biological_processpositive regulation of cell population proliferation
D0019730biological_processantimicrobial humoral response
D0019899molecular_functionenzyme binding
D0030574biological_processcollagen catabolic process
D0035578cellular_componentazurophil granule lumen
D0043231cellular_componentintracellular membrane-bounded organelle
D0043547biological_processpositive regulation of GTPase activity
D0044853cellular_componentplasma membrane raft
D0045121cellular_componentmembrane raft
D0045217biological_processcell-cell junction maintenance
D0050765biological_processnegative regulation of phagocytosis
D0062023cellular_componentcollagen-containing extracellular matrix
D0070062cellular_componentextracellular exosome
D0072672biological_processneutrophil extravasation
D0097029biological_processmature conventional dendritic cell differentiation
Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
ChainResidueDetails
ALEU53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. GIcfGDSGGPLI
ChainResidueDetails
AGLY189-ILE200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsACT_SITE: Charge relay system => ECO:0000255|PROSITE-ProRule:PRU00274
ChainResidueDetails
AHIS57
DHIS57
DASP102
DSER195
AASP102
ASER195
BHIS57
BASP102
BSER195
CHIS57
CASP102
CSER195

site_idSWS_FT_FI2
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN113
BASN113
CASN113
DASN113

site_idSWS_FT_FI3
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8757293, ECO:0007744|PDB:1FUJ
ChainResidueDetails
AASN159
BASN159
CASN159
DASN159

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
AASP102
ASER195
AHIS57

site_idCSA10
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
BASP102
BSER195
BHIS57
BGLY196

site_idCSA11
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
CASP102
CSER195
CHIS57
CGLY196

site_idCSA12
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
DASP102
DSER195
DHIS57
DGLY196

site_idCSA2
Number of Residues3
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
BASP102
BSER195
BHIS57

site_idCSA3
Number of Residues3
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
CASP102
CSER195
CHIS57

site_idCSA4
Number of Residues3
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
DASP102
DSER195
DHIS57

site_idCSA5
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
AASP102
ASER195
AGLY193
AHIS57

site_idCSA6
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
BASP102
BSER195
BGLY193
BHIS57

site_idCSA7
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
CASP102
CSER195
CGLY193
CHIS57

site_idCSA8
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
DASP102
DSER195
DGLY193
DHIS57

site_idCSA9
Number of Residues4
DetailsAnnotated By Reference To The Literature 1a0j
ChainResidueDetails
AASP102
ASER195
AHIS57
AGLY196

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PDB entries from 2024-07-17

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