1FU2

FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005179	molecular_function	hormone activity
A	0005576	cellular_component	extracellular region
B	0005179	molecular_function	hormone activity
B	0005576	cellular_component	extracellular region
C	0005179	molecular_function	hormone activity
C	0005576	cellular_component	extracellular region
D	0005179	molecular_function	hormone activity
D	0005576	cellular_component	extracellular region
E	0005179	molecular_function	hormone activity
E	0005576	cellular_component	extracellular region
F	0005179	molecular_function	hormone activity
F	0005576	cellular_component	extracellular region
G	0005179	molecular_function	hormone activity
G	0005576	cellular_component	extracellular region
H	0005179	molecular_function	hormone activity
H	0005576	cellular_component	extracellular region

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN B 501

Chain	Residue
B	HIS10
B	CL502

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN D 1501

Chain	Residue
D	HIS10
D	CL1502

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 502

Chain	Residue
B	ZN501

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 1502

Chain	Residue
D	LEU6
D	ZN1501

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN F 601

Chain	Residue
F	HIS10
F	CL602

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN H 1601

Chain	Residue
H	HIS10
H	CL1602

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL F 602

Chain	Residue
F	ZN601

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL H 1602

Chain	Residue
H	HIS10
H	ZN1601

---

Functional Information from PROSITE/UniProt

site_id	PS00262
Number of Residues	15
Details	INSULIN Insulin family signature. CCTSiCSlyqLenyC

Chain	Residue	Details
A	CYS6-CYS20

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Peptide: {"description":"Insulin A chain","featureId":"PRO_0000015821"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	116
Details	Peptide: {"description":"Insulin B chain","featureId":"PRO_0000015819"}

Chain

Residue

Details

---