1FRA

TERTIARY STRUCTURE OF ERABUTOXIN B IN AQUEOUS SOLUTION ELUCIDATED BY TWO-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0030550	molecular_function	acetylcholine receptor inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PROSITE/UniProt

site_id	PS00272
Number of Residues	19
Details	SNAKE_TOXIN Snake toxins signature. GCg..CPtvkpgikls.CCesE

Chain	Residue	Details
A	GLY40-GLU58

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Region: {"description":"Loop I","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Region: {"description":"Stretch between loop I and loop II","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	17
Details	Region: {"description":"Loop II","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	11
Details	Region: {"description":"Loop III","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	5
Details	Site: {"description":"Moderately important residue for binding to acetylcholine receptor","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	6
Details	Site: {"description":"Very important residue for binding to acetylcholine receptor","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	4
Details	Site: {"description":"Key residue for binding to acetylcholine receptor","evidences":[{"source":"UniProtKB","id":"P60775","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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