1FP2
CRYSTAL STRUCTURE ANALYSIS OF ISOFLAVONE O-METHYLTRANSFERASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0009717 | biological_process | isoflavonoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0033800 | molecular_function | isoflavone 7-O-methyltransferase activity |
| A | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAH A 1699 |
| Chain | Residue |
| A | GLY196 |
| A | HOH2001 |
| A | HOH2002 |
| A | HOH2014 |
| A | HOH2026 |
| A | HOH2031 |
| A | HOH2039 |
| A | HOH2047 |
| A | HOH2054 |
| A | ASP219 |
| A | ARG220 |
| A | ASP239 |
| A | MET240 |
| A | PHE241 |
| A | LYS253 |
| A | ILE255 |
| A | HMO2000 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HMO A 2000 |
| Chain | Residue |
| A | TYR25 |
| A | VAL118 |
| A | LEU123 |
| A | SER124 |
| A | TYR127 |
| A | PHE164 |
| A | TYR254 |
| A | HIS257 |
| A | ASN258 |
| A | ASN310 |
| A | SAH1699 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01020","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11224575","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FP2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11224575","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FP2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CIG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1kyw |
| Chain | Residue | Details |
| A | HIS257 |
