Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1860 |
| Chain | Residue |
| A | TRP358 |
| A | VAL420 |
| A | SER428 |
| A | HOH1965 |
| A | HOH2230 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 2860 |
| Chain | Residue |
| B | HOH2960 |
| B | HOH3107 |
| B | HOH3131 |
| B | GLY188 |
| B | TRP358 |
| B | VAL420 |
| B | SER428 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CAC A 1950 |
| Chain | Residue |
| A | TRP324 |
| A | CYS384 |
| A | LYS438 |
| A | ARG440 |
| A | GLY441 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CAC B 2950 |
| Chain | Residue |
| B | TYR83 |
| B | TRP324 |
| B | CYS384 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS96 |
| A | CYS101 |
| B | CYS96 |
| B | CYS101 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | TRP180 |
| A | ARG185 |
| A | CYS186 |
| A | SER228 |
| A | MET341 |
| A | PHE355 |
| A | SER356 |
| A | TRP358 |
| A | GLU363 |
| A | TRP449 |
| A | TYR477 |
| A | 14W810 |
| A | GOL1880 |
| A | HOH2034 |
| A | HOH2036 |
| A | HOH2066 |
| A | HOH2133 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | TRP180 |
| B | ALA183 |
| B | ARG185 |
| B | CYS186 |
| B | SER228 |
| B | MET341 |
| B | PHE355 |
| B | SER356 |
| B | GLY357 |
| B | TRP358 |
| B | GLU363 |
| B | TRP449 |
| B | TYR477 |
| B | 14W810 |
| B | GOL2880 |
| B | HOH2993 |
| B | HOH3073 |
| B | HOH3114 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 14W A 810 |
| Chain | Residue |
| A | GLN249 |
| A | PRO336 |
| A | VAL338 |
| A | TRP358 |
| A | GLU363 |
| A | HEM500 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 14W B 810 |
| Chain | Residue |
| B | GLN249 |
| B | VAL338 |
| B | TRP358 |
| B | GLU363 |
| B | HEM500 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1880 |
| Chain | Residue |
| A | ARG367 |
| A | ALA448 |
| A | TRP449 |
| A | HEM500 |
| A | HOH2001 |
| A | HOH2036 |
| A | HOH2216 |
| B | HOH3033 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 2880 |
| Chain | Residue |
| A | PHE462 |
| B | ARG367 |
| B | ALA448 |
| B | TRP449 |
| B | HEM500 |
| B | HOH3073 |
| B | HOH3093 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG185-TRP192 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | THR97 | |
| A | LEU102 | |
| B | THR97 | |
| B | LEU102 | |
| Chain | Residue | Details |
| A | LEU105 | |
| A | GLN478 | |
| B | LEU105 | |
| B | LEU250 | |
| B | TYR359 | |
| B | MET360 | |
| B | ILE364 | |
| B | LEU369 | |
| B | TRP449 | |
| B | ILE450 | |
| B | HIS463 | |
| A | LEU250 | |
| B | GLN478 | |
| A | TYR359 | |
| A | MET360 | |
| A | ILE364 | |
| A | LEU369 | |
| A | TRP449 | |
| A | ILE450 | |
| A | HIS463 | |
| Chain | Residue | Details |
| A | VAL187 | |
| B | VAL187 | |
| Chain | Residue | Details |
| A | PRO117 | |
| B | PRO117 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| A | CYS186 | |
| A | ARG189 | |
| A | GLU363 | |
| A | TRP358 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| B | CYS186 | |
| B | ARG189 | |
| B | GLU363 | |
| B | TRP358 | |
