1FLO

FLP Recombinase-Holliday Junction Complex I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003690	molecular_function	double-stranded DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005575	cellular_component	cellular_component
A	0006310	biological_process	DNA recombination
A	0008301	molecular_function	DNA binding, bending
A	0009009	molecular_function	site-specific recombinase activity
A	0015074	biological_process	DNA integration
A	0042150	biological_process	plasmid recombination
B	0003677	molecular_function	DNA binding
B	0003690	molecular_function	double-stranded DNA binding
B	0003697	molecular_function	single-stranded DNA binding
B	0005575	cellular_component	cellular_component
B	0006310	biological_process	DNA recombination
B	0008301	molecular_function	DNA binding, bending
B	0009009	molecular_function	site-specific recombinase activity
B	0015074	biological_process	DNA integration
B	0042150	biological_process	plasmid recombination
C	0003677	molecular_function	DNA binding
C	0003690	molecular_function	double-stranded DNA binding
C	0003697	molecular_function	single-stranded DNA binding
C	0005575	cellular_component	cellular_component
C	0006310	biological_process	DNA recombination
C	0008301	molecular_function	DNA binding, bending
C	0009009	molecular_function	site-specific recombinase activity
C	0015074	biological_process	DNA integration
C	0042150	biological_process	plasmid recombination
D	0003677	molecular_function	DNA binding
D	0003690	molecular_function	double-stranded DNA binding
D	0003697	molecular_function	single-stranded DNA binding
D	0005575	cellular_component	cellular_component
D	0006310	biological_process	DNA recombination
D	0008301	molecular_function	DNA binding, bending
D	0009009	molecular_function	site-specific recombinase activity
D	0015074	biological_process	DNA integration
D	0042150	biological_process	plasmid recombination

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PHS E -4

Chain	Residue
A	ARG191
A	LYS223
A	HIS305
A	ARG308
D	TYR343
E	DC-5
J	DT-3

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PHS G -4

Chain	Residue
B	ARG191
B	LYS223
B	HIS305
B	ARG308
C	TYR343
G	DC-5
L	DT-3

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PHS I -4

Chain	Residue
C	ARG191
C	HIS305
H	DT-3
I	DC-5

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PHS K -4

Chain	Residue
D	ARG191
D	HIS305
F	DT-3
K	DC-5

---

site_id	CTA
Number of Residues	6
Details	ACTIVE CATALYTIC SITE OF MONOMER A. Y343 IS DONATED BY MONOMER D.

Chain	Residue
A	ARG191
A	LYS223
A	HIS305
A	ARG308
A	TRP330
D	TYR343

---

site_id	CTB
Number of Residues	6
Details	ACTIVE CATALYTIC SITE OF MONOMER B. Y343 IS DONATED BY MONOMER C.

Chain	Residue
B	ARG308
B	TRP330
C	TYR343
B	ARG191
B	LYS223
B	HIS305

---

site_id	CTC
Number of Residues	6
Details	INACTIVE CATALYTIC SITE OF MONOMER C. Y343 IS DONATED BY MONOMER A.

Chain	Residue
C	ARG191
C	LYS223
C	HIS305
C	ARG308
C	TRP330
A	TYR343

---

site_id	CTD
Number of Residues	5
Details	INACTIVE CATALYTIC SITE OF MONOMER D. Y343 IS DONATED BY MONOMER B, IS DISORDERED.

Chain	Residue
D	ARG191
D	LYS223
D	HIS305
D	ARG308
D	TRP330

---

site_id	PHO
Number of Residues	4
Details	SCISSLE PHOSPHATES

Chain	Residue
E	PHS-4
G	PHS-4
K	PHS-4
I	PHS-4

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: O-(3'-phospho-DNA)-tyrosine intermediate => ECO:0000255|PROSITE-ProRule:PRU01247, ECO:0000269|PubMed:2211714

Chain	Residue	Details
A	TYR343
B	TYR343
C	TYR343
D	TYR343

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